AMT HYDROCHLORIDE
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- CAS-Nr.
- 21463-31-0
- Englisch Name:
- AMT HYDROCHLORIDE
- Synonyma:
- 4H-1;AMT HCL;AMT HYDROCHLORIDE;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL;2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE;5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE;4H-1,3-Thiazin-2-amine, 5,6-dihydro-6-methyl-, hydrochloride (1:1)
- CBNumber:
- CB3266443
- Summenformel:
- C5H10N2S.ClH
- Molgewicht:
- 166.67
- MOL-Datei:
- 21463-31-0.mol
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AMT HYDROCHLORIDE Eigenschaften
- Schmelzpunkt:
- 146-150°C
- storage temp.
- 0-6°C
- L?slichkeit
- DMF: >8 mg/ml; DMSO: >16 mg/ml; Ethanol: >25 mg/ml; Water: >25 mg/ml
- Aggregatzustand
- A crystalline solid
- Wasserl?slichkeit
- Soluble to 10 mM in water
AMT HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
AMT is a potent, relatively selective inhibitor of iNOS with a K
i of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations; the IC
50 values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.
Chemische Eigenschaften
white to off-white powder
Biologische Aktivit?t
Potent, selective and reversible inhibitor of iNOS (IC 50 = 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively).
AMT HYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
AMT HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 47)Lieferanten
- 5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZIN-2-AMINE, HYDROCHLORIDE
- AMT HYDROCHLORIDE
- AMT HCL
- 2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HYDROCHLORIDE
- 2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE HCL
- 4H-1
- 4H-1,3-Thiazin-2-amine, 5,6-dihydro-6-methyl-, hydrochloride (1:1)
- 21463-31-0
- C5H11ClN2S
- C5H10N2SHCl
- Enzyme Inhibitors
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors by Enzyme
- Biochemicals and Reagents
- BioChemical
- L to O
- Nitric Oxide Synthase (iNOS)
