R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen. S24/25:Berührung mit den Augen und der Haut vermeiden. S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Lisinopril is an angiotensin converting enzyme inhibitor structurally related to enalaprilat.
It is reportedly useful in the management of hypertension and congestive heart failure.
Chemische Eigenschaften
White to Off-White Crystalline Powder
Allgemeine Beschreibung
Lisinopril, 1-[N2-[S-1-carboxy-3-phenylpropyl]-L-lysyl]-L-proline dihydrate (Prinivil, Zestril), is alysine derivative of enalaprilat, the active metabolite ofenalapril. Like all ACE inhibitors, it is an active site-directedinhibitor of the enzyme, with the zinc ion used in an effectivebinding interaction at a stoichiometric ratio of 1:1. The pharmacologicaleffects of lisinopril are similar to those of captopriland enalapril.
Clinical Use
Many new ACE inhibitors became available for the treatmentof hypertension following the clinical effectivenessof enalapril. Enalapril is a non–thiol-containing ACE inhibitordevoid of the side effects of rash and loss of thesense of taste characteristic of the thiol-containing compoundcaptopril. With the exception of the phosphoruscontainingfosinopril, these antihypertensive agents havea 2-, like the prototypical drug captopril,are used in the treatment of mild-to-moderate hypertension,either alone or in conjunction with diuretics orcalcium channel blockers.
Lisinopril Dihydrate Upstream-Materialien And Downstream Produkte
Lisinopril DihydrateQ: What is
Lisinopril Dihydrate Q: What is the CAS Number of
Lisinopril Dihydrate Q: What is the storage condition of
Lisinopril Dihydrate
"Lisinopril for system suitability (Y0001235)"Q: What is
"Lisinopril for system suitability (Y0001235)" Q: What is the CAS Number of
"Lisinopril for system suitability (Y0001235)"