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BICALUTAMIDE-D4

BICALUTAMIDE-D4 Struktur
1185035-71-5
CAS-Nr.
1185035-71-5
Englisch Name:
BICALUTAMIDE-D4
Synonyma:
Casodex-d4;ICI-176334-d4;(CI-176334-D4;BICALUTAMIDE-D4;[2H4]-Bicalutamide;Bicalutamide Impurity 17;N-[4-Cyano-3-trifluoromethyl)phenyl]- 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4;N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl-2,3,5,6-d4)sulfonyl)-2-hydroxy-2-methylpropanamide;Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl-2,3,5,6-d4)sulfonyl]-2-hydroxy-2-methyl-
CBNumber:
CB2737393
Summenformel:
C18H10D4F4N2O4S
Molgewicht:
434.4
MOL-Datei:
1185035-71-5.mol

BICALUTAMIDE-D4 Eigenschaften

Schmelzpunkt:
192-1940C
Siedepunkt:
650.308±55.00 °C(Press: 760.00 Torr)(predicted)
Dichte
1.522±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. 
-20°C Freezer
L?slichkeit
Chloroform (Slightly, Heated), Methanol (Slightly, Sonicated)
pka
11.492±0.29(predicted)
Aggregatzustand
Solid
Farbe
White to Off-White

Sicherheit

BICALUTAMIDE-D4 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Bicalutamide-d4 is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.

Chemische Eigenschaften

BICALUTAMIDE-D4 is White Solid

Verwenden

BICALUTAMIDE-D4 is used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0

BICALUTAMIDE-D4 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BICALUTAMIDE-D4 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 46)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Standardpharm Co. Ltd. 		86-714-3992388
overseasales1@yongstandards.com United States 14332 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Chemsky（shanghai）International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
Cato Research Chemicals Inc. 020-81960175
min.he@cato-chem.com China 1955 55
Hubei Yangxin Medical Technology Co., Ltd. 15374522761
 3003392093@qq.com China 8875 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
 sales@rrkchem.com China 57422 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 020-36607679 17825480238
 3008233746@qq.com China 9934 12
Jinan blalong chemical co. LTD 2710913286@.com
 1513643261@qq.com China 14246 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Manhag Testing Technology Co., Ltd 020-3846 2365 19110442770
 458677837@qq.com China 7775 58
  • BICALUTAMIDE-D4
  • Casodex-d4
  • ICI-176334-d4
  • N-[4-Cyano-3-trifluoromethyl)phenyl]- 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4
  • (CI-176334-D4
  • Bicalutamide Impurity 17
  • [2H4]-Bicalutamide
  • Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl-2,3,5,6-d4)sulfonyl]-2-hydroxy-2-methyl-
  • N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl-2,3,5,6-d4)sulfonyl)-2-hydroxy-2-methylpropanamide
  • 1185035-71-5
  • C18H10D4F4N2O4S
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Isotope Labelled Compounds
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