ANTI-APOPTOSIS REPRESSOR WITH CARD (CT) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-Arc (C-terminal) antibody produced in rabbit has been used in immunoblotting.
Allgemeine Beschreibung
Activity-regulated cytoskeleton-associated protein (ARC) encodes a growth factor and is an immediate early gene (IEG) that is enriched in brain. It is also known as Arg3.1.
Biochem/physiol Actions
Activity-regulated cytoskeleton-associated protein (ARC) is associated with synaptic plasticity and normal development in the central nervous system (CNS) induced by neuronal activity. Arc expression is tightly controlled by neuronal activity and its mRNA is rapidly localized to neuronal dendrites and spines where it undergoes local translation. Arc induction is required for late long-term potentiation (LTP) and memory consolidation, as well as LTP-induced cofilin phosphorylation and F-actin stabilization. Arc is known to regulate endocytosis of AMPA receptors mediated interaction with endophilin 3 and dynamin 2, notch signalling and spine morphology.
ANTI-APOPTOSIS REPRESSOR WITH CARD (CT) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte