Anti-HsT771 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project
(www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these
protocols and other useful information about Prestige Antibodies and the HPA, visit .
Allgemeine Beschreibung
Piezo-type mechanosensitive ion channel component 2 (PIEZO2) is encoded by the mapped to human chromosome 18p. It is mainly expressed in the urinary bladder, lung, dorsal root ganglia and in Merkel cells in the skin.
Biochem/physiol Actions
Piezo-type mechanosensitive ion channel component 2 (PIEZO2) functions as a non-selective cation channel. The encoded protein is a mechanosensitive ion channel and is involved in light-touch mechanosensation. PIEZO2 is also a mechanotransduction channel for proprioception. Dominant mutations causing gain of function in PIEZO2 result in Gordon syndrome/distal arthrogryposis and Marden-Walker syndrome. Recessive mutations in this gene lead to distal arthrogryposis with distal muscle weakness, scoliosis and proprioception problems.
Anti-HsT771 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
