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DICLOFENAC-D4

DICLOFENAC-D4 Struktur
153466-65-0
CAS-Nr.
153466-65-0
Englisch Name:
DICLOFENAC-D4
Synonyma:
D4-Diclofenac;DICLOFENAC-D4;[2H4]-Diclofenac;Diclofenac-D4 (Major);DICLOFENAC-D4 (PHENYL-D4);2-((2,6-Dichlorophenyl)aminobenzeneacetic Acid-d4,;2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]aceticaci;2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid;Diclofenac D4Q: What is Diclofenac D4 Q: What is the CAS Number of Diclofenac D4 Q: What is the storage condition of Diclofenac D4 Q: What are the applications of Diclofenac D4
CBNumber:
CB1677920
Summenformel:
C14H11Cl2NO2
Molgewicht:
296.15
MOL-Datei:
153466-65-0.mol

DICLOFENAC-D4 Eigenschaften

Schmelzpunkt:
157-159°C
storage temp. 
-20°C Freezer
L?slichkeit
DMSO: 35 mg/ml,Ethanol: 35 mg/ml,PBS (pH 7.2): 6 mg/ml
Aggregatzustand
A solid
Farbe
White to off-white
Wasserl?slichkeit
Water: 50 mg/ml
CAS Datenbank
153466-65-0

Sicherheit

DICLOFENAC-D4 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Diclofenac-d4 is intended for use as an internal standard for the quantification of diclofenac (Item Nos. 70680 | 22983) by GC- or LC-MS. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.9-2.7 and 1.5-20 μM, for human COX-1 and COX-2, respectively). It is also an active metabolite of diclofenac methyl ester and diclofenac amide . Diclofenac inhibits release of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) induced by A23187 in isolated rat peritoneal neutrophils and macrophages (IC50s = 60 and 10 μM, respectively). Transdermal administration of diclofenac inhibits carrageenan-induced paw edema in rats. Formulations containing diclofenac have been used in the treatment of pain associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Chemische Eigenschaften

Off-White Crystalline Solid

Verwenden

Labeled Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. 92% overall isotopic purity. A representative lot was 75% d4, 23% d3 and 2 % d2

DICLOFENAC-D4 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


DICLOFENAC-D4 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 56)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
TargetMol Chemicals Inc.
+8613564774135
zijue.cai@tsbiochem.com United States 19881 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 94657 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412
3001272453@qq.com China 5047 50
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826
market@aladdin-e.com China 25003 65
Cato Research Chemicals Inc. 020-81960175
min.he@cato-chem.com China 1955 55
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396
sales@chem-strong.com China 18070 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656
greensnown@163.com China 9906 50

153466-65-0()Verwandte Suche:


  • DICLOFENAC-D4
  • DICLOFENAC-D4 (PHENYL-D4)
  • 2-((2,6-Dichlorophenyl)aminobenzeneacetic Acid-d4,
  • Diclofenac-D4 (Major)
  • 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]acetic acid
  • D4-Diclofenac
  • [2H4]-Diclofenac
  • Diclofenac D4Q: What is Diclofenac D4 Q: What is the CAS Number of Diclofenac D4 Q: What is the storage condition of Diclofenac D4 Q: What are the applications of Diclofenac D4
  • 2-[2,3,4,5-tetradeuterio-6-(2,6-dichloroanilino)phenyl]aceticaci
  • 153466-65-0
  • C14H7D4Cl2NO2
  • C14H7Cl2D4NO2
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
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