Trioxysalen Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R34:Verursacht Ver?tzungen.
R40:Verdacht auf krebserzeugende Wirkung.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Chemische Eigenschaften

White to slightly beige crystalline powder

Verwenden

Trioxsalen has been used:

• to induce small deletion mutations in worms
• in combination with ultraviolet A (UVA)
• to induce interstrand crosslinks (ICLs) in DNA
• for the preparation and photoactivation of trimethyl psoralen

Definition

ChEBI: 7H-Furo[3,2-g]chromen-7-one in which positions 2, 5, and 9 are substituted by methyl groups. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered orally in conjunction with UV-A for phot therapy treatment of vitiligo. After photoactivation it creates interstrand cross-links in DNA, inhibiting DNA synthesis and cell division, and can lead to cell injury; recovery from the cell injury may be followed by increased melanisation of the epidermi .

Indications

Trioxsalen (Trisoralen) followed by UVA exposure is used to repigment vitiliginous areas and in photochemotherapy.

l?uterung methode

Purify trioxsalen by recrystallisation from CHCl3. If too impure, it is fractionally crystallised from CHCl3/pet ether (b 30-60o) using Norit and finally crystallised from CHCl3 alone to give colourless prisms, m 234.5-235o. It is a photosensitiser so it should be stored in the dark. [UV: Kaufmann J Org Chem 26 117 1961, Baeme et al. J Chem Soc 2976 1949, Beilstein 19/4 V 472.]

Trioxysalen Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Trioxysalen Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15352	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9639	58
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	8670	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
SUZHOU SENFEIDA CHEMICAL CO.,LTD	+86-0512-83500002 +8615195660023	sales@senfeida.com	China	23046	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33338	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58

3902-71-4(Trioxysalen)Verwandte Suche:

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• TRISORALEN
• TRIOXSALEN
• TRIOXYSALEN
• 2',4,8-Trimethylpsoralen
• 2,5,9-Trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one
• 2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one
• 2,5,9-TRIMETHYL-FURO[3,2-G]BENZOPYRAN-7-ONE
• 2,5,9-TRIMETHYL-FUROL[3,2-G]BENZOPYRAN-7-ONE
• 2,5,9-TRIMETHYLPSORALEN
• TRIOXSALEN, FOR FLUORESCENCE
• 4,5',8-Trimethylpsoralen, 97.50%
• TRIOXSALEN,USP
• TRIOXSALEN (4,5,8-TRIMETHYLPSORALEN)
• 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one, 4,5μ,8-Trimethylpsoralen, TMP, Trisoralen
• 4,2',8-Trimethylpsoralen
• 4,5',8-Trimethylpsoralen,97.5%
• 4,5,8-Trimethylpsoralen ,99%
• Trioxsalen (200 mg)
• TMP 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one 4,5',8-Trimethylpsoralen Trisoralen
• 2’,4,8-trimethylpsoralen
• 2-g)(1)benzopyran-7-one,2,5,9-trimethyl-7h-furo(
• 2-g][1]benzopyran-7-one,2,5,9-trimethyl-7h-furo[
• 4,5',8-Trimethylpsoralene
• 5-Benzofuranacrylic acid, 6-hydroxy-beta,2,7-trimethyl-, delta-lactone
• 6-hydroxy-beta,2,7-trimethyl-5-benzofuranacrylicacidgamma-lactone
• 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-
• Benzofuranacrylic acid,6-hydroxy-b,2,7-trimethyl-,
• Elder 8011
• LACTONE
• NSC-71047
• psoralen,4,5’,8-trimethyl-
• Trimethylpsoralen
• Trioxalen
• Trioxsale
• TRIOXSALIN
• Trixsalen
• 4,5',8-TRIMETHYLPSORALEN
• 4,5,8-TRIMETHYLPSORALEN
• )-7-Cyano-17-hydroxy-3-oxo-pregna-4,9(11)-diene-21-carboxylic acid &gamma
• 3,13-Dihydroxy-13,17-secoandrost-5-en-17-oic Acid &delta
• 2,3-Dideoxy-2-methylene-D-glycero-D-galacto-nononic acid &gamma
• 5-O-(1-Methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-D-ribonic Acid &gamma
• 11,12-Dihydro-11-hydroxyretinoic Acid &delta
• 17-Hydroxy-3-oxo-17&alpha
• -pregna-4,20-diene-21-carboxylic Acid &gamma
• Homogentisic Acid &gamma
• N-Boc L-Serine b-Lactone ([(3S)-2-oxo-3-oxetanyl]-1,1-dimethylethyl Ester Carbamic Acid, |N-(tert-Butoxycarbonyl)-L-serine ß
• 4-tert-Butyldimethylsilyl-6&rsquo
• -carboxy-5&rsquo
• -hydroxy Simvastatin &gamma
• rioxsalen
• TRIOXSALEN ISO 9001：2015 REACH
• TrioxsalenQ: What is Trioxsalen Q: What is the CAS Number of Trioxsalen Q: What is the storage condition of Trioxsalen Q: What are the applications of Trioxsalen
• 2,5,9-trimethylfuro[3,2-g]chromen-7-one
• Trioxsalen (1693009)
• 16-Deacetylfusidic Acid &gamma
• 2,5,9-trimethyl-7-furo[3,2-g][1]benzopyranone
• 6-Hydroxy-5-iodo-7-oxabicyclo[2.2.1]heptane-2-carboxylic Acid &gamma