CALP3 (trifluoroacetate salt) Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
CALP3 is a calcium-like peptide that contains the first eight residues of CALP2, which is a 12-residue peptide that interacts with EF hand motif 4 in human calmodulin to activate it in the absence of calcium. It acts as a cell-permeable inhibitor of calcium influx through glutamate receptor channels in cultured rat neocortical neurons (IC
50 = 37.25 μM) thereby inhibiting excitatory cytotoxicity (IC
50 = 50.97 μM) and apoptosis (IC
50 = 33.41 μM).
CALP3 (trifluoroacetate salt) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte