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CRT-0066101 hydrochloride

CRT-0066101 hydrochloride Struktur
1290629-45-6
CAS-Nr.
1290629-45-6
Englisch Name:
CRT-0066101 hydrochloride
Synonyma:
CRT 0066101 hydrochloride;CRT-0066101 hydrochloride;CRT0066101 (hydrochloride)
CBNumber:
CB02667894
Summenformel:
C18H25Cl3N6O
Molgewicht:
447.79
MOL-Datei:
1290629-45-6.mol

CRT-0066101 hydrochloride Eigenschaften

Sicherheit

CRT-0066101 hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT0066101 is an inhibitor of all three PKD isoforms (IC50s = 1, 2.5, and 2 nM for PKD1, PKD2, and PKD3, respectively). It exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCα, PKBα, MEK, ERK, c-Raf, c-Src, and c-Abl. It can block cell proliferation, induce apoptosis, and reduce the viability of pancreatic cancer cells both in vitro and in vivo.[Cayman Chemical]

CRT-0066101 hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CRT-0066101 hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 21)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054
trendseenbio@gmail.com China 11681 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
DC Chemicals 021-58447131 13564518121
sales@dcchemicals.com China 9409 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
Absin Bioscience Inc. 021-38015121 18438616290
wulan@absin.cn China 24731 58
Cayman Chemical Company (800)364-9897
Caymanname@qq.com CHINA 21570 58

  • CRT0066101 (hydrochloride)
  • CRT-0066101 hydrochloride
  • CRT 0066101 hydrochloride
  • 1290629-45-6
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