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(S)-Lisofylline

(S)-Lisofylline Struktur
100324-80-9
CAS-Nr.
100324-80-9
Englisch Name:
(S)-Lisofylline
Synonyma:
(S)-Lisofylline;(S)-Lisophylline;(S)-Lisofylline Exclusive;(S)-Lisofylline, 10 mM in DMSO;(S)Lisofylline,(S) Lisofylline;1-[(5S)-5-hydroxyhexyl]-3,7-dimethylpurine-2,6-dione;1H-Purine-2,6-dione, 3,7-dihydro-1-[(5S)-5-hydroxyhexyl]-3,7-dimethyl-
CBNumber:
CB02589835
Summenformel:
C13H20N4O3
Molgewicht:
280.32
MOL-Datei:
100324-80-9.mol

(S)-Lisofylline Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
≤15mg/ml in ethanol;3mg/ml in DMSO;12mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
Farbe
Off-white to light yellow

Sicherheit

(S)-Lisofylline Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

LSF, a chiral metabolite of pentoxifylline, acts as a potent anti-inflammatory agent. (S)-LSF is the pharmacologically inactive optical enantiomer of (R)-LSF, the biologically active isomer. When metabolized by isolated human liver cells, pentoxifylline is exclusively reduced to (S)-LSF in the cytosol, while reduction in liver microsomes is 85% stereoselective in favor of (S)-LSF formation. Thus, pentoxifylline is an inefficient prodrug for the delivery of therapeutically relevant lisofylline.

Verwenden

LSF, a chiral metabolite of pentoxifylline, acts as a potent anti-inflammatory agent. (S)-LSF is the pharmacologically inactive optical enantiomer of (R)-LSF, the biologically active isomer. When metabolized by isolated human liver cells, pentoxifylline is exclusively reduced to (S)-LSF in the cytosol, while reduction in liver microsomes is 85% stereoselective in favor of (S)-LSF formation. Thus, pentoxifylline is an inefficient prodrug for the delivery of therapeutically relevant lisofylline.[Cayman Chemical]

(S)-Lisofylline Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(S)-Lisofylline Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 30)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32159 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 12952 65
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
 order@med-bio.cn China 8140 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24641 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 11973 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026
Sales@sangon.com China 47255 58
Cayman Chemical Company 800-3649897
Caymanname@qq.com China 21643 58
ApexBio Technology --
 sales@apexbt.com United States 6251 58
  • (S)-Lisofylline
  • 1H-Purine-2,6-dione, 3,7-dihydro-1-[(5S)-5-hydroxyhexyl]-3,7-dimethyl-
  • (S)-Lisofylline Exclusive
  • 1-[(5S)-5-hydroxyhexyl]-3,7-dimethylpurine-2,6-dione
  • (S)-Lisophylline
  • (S)Lisofylline,(S) Lisofylline
  • (S)-Lisofylline, 10 mM in DMSO
  • 100324-80-9
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