932-53-6
中文名稱(chēng)
6-氮雜胸腺嘧啶
英文名稱(chēng)
6-AZATHYMINE
CAS
932-53-6
EINECS 編號(hào)
213-253-9
分子式
C4H5N3O2
MDL 編號(hào)
MFCD00006457
分子量
127.1
MOL 文件
932-53-6.mol
更新日期
2025/01/19 20:16:12
932-53-6 結(jié)構(gòu)式
基本信息
中文別名
6-氮雜胸腺嘧啶6-吖胸嘧啶
6-氮胸嘧啶
英文別名
1,2,4-TRIAZINE-3,5(2H,4H)-DIONE, 6-METHYL-3,5-DIHYDROXY-6-METHYL-1,2,4-TRIAZINE
6-AZA-2,4-DIHYDROXY-5-METHYL-PYRIMIDINE
6-AZA-5-METHYLURACIL
6-AZATHYMINE
6-METHYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE
4h)-dione,6-methyl-as-triazine-5(2h
4-triazine-3,5(2h,4h)-dione,6-methyl-2
5-Methyl-6-azauracil
6-Methyl-1,2,4-triazine-3,5-dione
6-methyl-as-triazine-3,5-(2h,4h)-dione
6-Methyl-as-triazine-3,5(2H,4H)-dione
6-methyl-as-triazine-3,5-diol
ai3-50849
as-Triazine-3,5(2H,4H)-dione, 6-methyl-
As-triazine-3,5-diol, 6-methyl-
USAF cb-28
usafcb-28
6-Azathymine,98%
6-METHYL-S-TRIAZINE-3,5-DIONE
所屬類(lèi)別
生物化工：核苷酸及其類(lèi)似物物理化學(xué)性質(zhì)
熔點(diǎn)210-212°C
沸點(diǎn)235.85°C (rough estimate)
密度1.4748 (rough estimate)
折射率1.5000 (estimate)
酸度系數(shù)(pKa)7.6(at 25℃)
形態(tài)粉末晶體
顏色白色到近乎白色
Merck14,903
BRN126863
InChIKeyXZWMZFQOHTWGQE-UHFFFAOYSA-N
CAS 數(shù)據(jù)庫(kù)932-53-6(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H335-H319-H302-H315
安全說(shuō)明S22-S24/25
RTECS號(hào)XY8050000
海關(guān)編碼2934.10.9000
危險(xiǎn)等級(jí)IRRITANT
知名試劑公司產(chǎn)品信息
Alfa Aesar
6-氮雜胸腺嘧啶,98%6-Azathymine, 98%(932-53-6)
TCI Shanghai
6-氮雜胸腺嘧啶6-Azathymine,>98.0%(LC)(T)(932-53-6)
6-氮雜胸腺嘧啶價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | L06762 | 6-氮雜胸腺嘧啶, 98% 6-Azathymine, 98% | 932-53-6 | 5g | 1295元 |
| 2024/11/08 | L06762 | 6-氮雜胸腺嘧啶, 98% 6-Azathymine, 98% | 932-53-6 | 25g | 5172元 |
| 2024/11/08 | HY-136559 | 6-氮雜胸腺嘧啶 6-Azathymine | 932-53-6 | 100mg | 600元 |
常見(jiàn)問(wèn)題列表
生物活性
6-Azathymine，胸腺嘧啶的 6-氮類(lèi)似物，是一種有效的 D-3-氨基異丁酸酯-丙酮酸氨基轉(zhuǎn)移酶 (D-3-aminoisobutyrate-pyruvate aminotransferase) 抑制劑。6-Azathymine 可抑制 DNA 的生物合成，并具有抗菌和抗病毒活性。體外研究
6-Azathymine is a competitive antagonist of the growth of Streptococcus faecalis (8043) and several other strains of microorganisms. Studies of the mechanism of action of 6-Azathymine reveal that S. faecalis can convert the analog to the corresponding deoxyriboside, azathymidine.
體內(nèi)研究
The administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. Following the administration of 6-Azathymine-5- 14 C to mice, radioactivity is found in all tissues investigated, not only in the form of free Azathymine, but also as metabolic derivatives.