午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

返回ChemicalBook首頁>CAS數(shù)據(jù)庫列表>59-42-7

59-42-7

中文名稱 去氧腎上腺素堿
英文名稱 Phenylephrine
CAS 59-42-7
EINECS 編號(hào) 200-424-8
分子式 C9H13NO2
MDL 編號(hào) MFCD00044749
分子量 167.21
MOL 文件 59-42-7.mol
更新日期 2025/01/07 18:51:26
59-42-7 結(jié)構(gòu)式 59-42-7 結(jié)構(gòu)式

基本信息

中文別名
3-羥基-alpha-((甲基氨基)甲基)-芐醇
去氧腎上腺素堿
去羥腎上腺素
去氧腎上腺
新交感酚
新辛內(nèi)井林
英文別名
3-(1-HYDROXY-2-METHYLAMINO-ETHYL)PHENOL
L-PHENYLEPHRINE
(-)-PHENYLEPHRINE
PHENYLEPHRINE BASE
(-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol
(-)-m-hydroxy-alpha-(methylaminomethyl)benzylalcohol
(-)-m-oxedrine
(R)-3-Hydroxy-alpha-[(methylamino)methyl]benzenemethanol hydrochloride
(r)-benzenemethano
(r)-phenylephrine
Adrianol
Ak-dilate
Ak-nefrin
Alcon efrin
Benzyl alcohol, m-hydroxy-alpha-((methylamino)methyl)-, (-)-
Biomydrin
component of Cerose dm
component of Comhist
component of Cyclomydril
component of Decongestant
所屬類別
分析化學(xué):藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品

物理化學(xué)性質(zhì)

熔點(diǎn)171°C
沸點(diǎn)295.79°C (rough estimate)
密度1.1222 (rough estimate)
折射率-55.5 ° (C=5, 1mol/L HCl)
儲(chǔ)存條件-20°C Freezer, Under inert atmosphere
溶解度Slightly soluble in water, sparingly soluble in methanol, slightly soluble in ethanol (96 per cent). It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxides.
酸度系數(shù)(pKa)pKa 8.9 (Uncertain)
形態(tài)neat
顏色白色至灰白色
CAS 數(shù)據(jù)庫59-42-7(CAS DataBase Reference)

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
警示詞危險(xiǎn)
危險(xiǎn)性描述H302-H315-H318-H335
危險(xiǎn)品標(biāo)志Xn
危險(xiǎn)類別碼R22-R36/37/38
安全說明S26-S36-S45
RTECS號(hào)DO7175000
海關(guān)編碼2922.19.7000
毒害物質(zhì)數(shù)據(jù)59-42-7(Hazardous Substances Data)
毒性LD50 oral in rat: 350mg/kg

應(yīng)用領(lǐng)域

用途一
擬腎上腺素藥物,用于外科手術(shù)延長局部麻醉時(shí)間、鼻粘膜充血、急性低血壓、感染中毒性及過敏性休克等癥

知名試劑公司產(chǎn)品信息

去氧腎上腺素堿價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08HY-B0769去氧腎上腺素堿
Phenylephrine
59-42-7500mg500元
2024/11/08P0395L-苯腎上腺素
L-Phenylephrine
59-42-75G720元
2024/11/08HY-B0769去氧腎上腺素堿
Phenylephrine
59-42-710mM * 1mLin DMSO550元

常見問題列表

生物活性
(R)-(-)-Phenylephrine是選擇性的α1-腎上腺素受體激動(dòng)劑,主要用作減充血?jiǎng)?/span>
體外研究

(R)-(-)-Phenylephrine is a selective α 1 -adrenoceptor agonist with pK i values of 5.86, 4.87 and 4.70 for α 1D , α 1B and α 1A receptors respectively. Phenylephrine promotes cardiac fibroblast proliferation. Phenylephrine activates CaN and evokes NFAT3 nuclear translocation. It suggests that the Ca( 2+ )/CaN/NFAT pathway mediates phenylephrine -induced cardiac fibroblast proliferation, and this pathway might be a possible therapeutic target in cardiac fibrosis.

體內(nèi)研究

Perfusion of hearts with 100 μM phenylephrine causes a rapid (maximal at 10 min) 12-fold activation of two p38-MAPK isoforms. α 1 -adrenoceptor agonists such as phenylephrine increase the contractility of the heart. Phenylephrine also activates SAPKs/JNKs in neonatal ventricular myocytes. Phenylephrine could increase the alveolar fluid clearance in high tidal volume-ventilated rats and accelerate the absorption of pulmonary edema.

"59-42-7" 相關(guān)產(chǎn)品信息
671-16-9 143390-89-0 100-51-6 474-25-9 1914-99-4 99-76-3 77-86-1 61-76-7 552-45-4 60-12-8 99-98-9 3094-09-5 128-13-2 96-33-3 74-83-9 94-07-5 329-65-7 485-49-4