490-78-8
中文名稱
2,5-二羥基苯乙酮
英文名稱
2',5'-Dihydroxyacetophenone
CAS
490-78-8
EINECS 編號
207-716-4
分子式
C8H8O3
MDL 編號
MFCD00002343
分子量
152.15
MOL 文件
490-78-8.mol
更新日期
2025/04/09 08:47:36
490-78-8 結構式
基本信息
中文別名
2,5-二羥基苯乙酮2',5'-二羥基苯乙酮
2,5-二羥基乙酰苯
2,5-二羥苯乙酮
2-乙醯氫醌
2',5'-二羥基苯乙酮, 98+%
英文別名
1-(2,5-DIHYDROXYPHENYL)ETHAN-1-ONE1-(2,5-DIHYDROXYPHENYL)ETHANONE
2',5'-DIHYDROXYACETOPHENONE
2,5-DIHYDROXYACETOPHENONE
2,5-DIHYDROXYPHENYL METHYL KETONE
2-ACETYL-1,4-DIHYDROXYBENZENE
2-ACETYLHYDROQUINONE
ACETYLQUINOL
QUINACETOPHENONE
1-(2,5-dihydroxyphenyl)-ethanon
1-Acetyl-2,5-dihydroxybenzene
2,5-Dihydroxy-1-acetylbenzene
2’,5’-dihydroxy-acetophenon
Acetophenone, 2',5'-dihydroxy-
Acetylhydroquinone
2',5'-Dihydroxyacetophenone 2-Acetylhydroquinone
2,5-Dihydroxyacetophenone, 98+%
2-Acethylhydroquinone
Ethanone, 1-(2,5-dihydroxyphenyl)-
2,5-DIHYDROXYACETOPHENONE extrapure
所屬類別
化學試劑：芳香酮物理化學性質
外觀性狀淡黃綠色針狀結晶。熔點202-203℃。溶于醇，難溶于醚和苯，幾乎不溶于冷水。在堿溶液中呈黃色，遇三氧化鐵呈藍色。能升華。
熔點204-206 °C(lit.)
沸點234.6°C (rough estimate)
密度1.2143 (rough estimate)
折射率1.4447 (estimate)
儲存條件Store below +30°C.
溶解度dioxane: 50 mg/mL, clear
酸度系數(pKa)9.86±0.18(Predicted)
形態(tài)晶體或結晶粉末
顏色黃色至黃綠色
水溶解性insoluble
BRN637903
InChIKeyWLDWSGZHNBANIO-UHFFFAOYSA-N
LogP1.274 (est)
安全數據
警示詞警告
危險性描述H315-H319-H335
危險品標志Xi
危險類別碼R36/37/38
安全說明S26-S36
WGK Germany3
RTECS號AM7700000
Hazard NoteIrritant
TSCAYes
海關編碼29145000
2,5-二羥基苯乙酮價格(試劑級)
| 報價日期 | 產品編號 | 產品名稱 | CAS號 | 包裝 | 價格 |
| 2025/02/08 | HY-W001174 | 2,5-二羥基苯乙酮 2,5-Dihydroxyacetophenone | 490-78-8 | 100mg | 550元 |
| 2025/02/08 | XW04907882 | 2‘,5‘-二羥基苯乙酮 2',5'-dihydroxyacetophenone;acetylquinol;2,5-dihydroxyacetophenone;quinacetophenone;2-acetylhydroquinone;2-acetyl-1,4-dihydroxybenzene;2,5-dihydroxyphenyl methyl ketone | 490-78-8 | 25G | 90元 |
| 2025/02/08 | HY-W001174 | 2,5-二羥基苯乙酮 2,5-Dihydroxyacetophenone | 490-78-8 | 10mM * 1mLin DMSO | 610元 |
常見問題列表
生物活性
2',5'-Dihydroxyacetophenone (DHAP, 2-Acetylhydroquinone, Quinacetophenone) 是二羥基苯乙酮異構體的混合物，用于食品調味。2',5'-Dihydroxyacetophenone 通過抑制 iNOS 的表達來顯著抑制 NO 的產生。2',5'-Dihydroxyacetophenone 可通過阻斷 ERK1/2 和 NF-κB 信號通路來顯著地降低促炎細胞因子 TNF-α 和 IL-6 的表達水平。靶點
| Target | Value |
|
iNOS
() | |
|
ERK1/2
() | |
|
NF-κB
() | |
|
TNF-α
() | |
|
IL-6
() |
體外研究
2,5-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression and significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 via the down-regulation of their mRNA expression in LPS-stimulated RAW264.7 cells. 2,5-Dihydroxyacetophenone potently inhibits the phosphorylation of extracellular signal-related kinase (ERK) 1/2 and the nuclear translocation of nuclear factor-κB (NF-κB) p65 in LPS-stimulated cells.