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118102-98-0

中文名稱 (D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
英文名稱 (D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
CAS 118102-98-0
更新日期 2025/01/07 10:41:58
118102-98-0 結構式 118102-98-0 結構式

基本信息

中文別名
甲狀腺激素相關肽[D-TRP12,TYR34]-PTH (7-34) AMIDE (BOVINE)
甲狀旁腺激素 [DTRP12, TYR34]-PTH(7-34), -PARATHYROID HOR
(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE) TRIFLUOROACETATE SALT
英文別名
THYROID, BOVINE
D-Trp12,Tyr34]-bPTH-(7-34)NH2
(D-Trp12,Tyr34)-pTH (7-34) amide
(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
PHE-MET-HIS-ASN-LEU-D-TRP-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-TYR-NH2
H-PHE-MET-HIS-ASN-LEU-D-TRP-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-TYR-NH2

物理化學性質

儲存條件-15°C
溶解度Soluble in DMSO
形態(tài)Solid
顏色White to off-white
(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2024/11/08HY-P2426(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
118102-98-01mg720元
2024/11/08HY-P2426(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
118102-98-05mg1800元
2024/11/08HY-P2426(D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
118102-98-010mg2800元

常見問題列表

生物活性
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) 是一種有效的競爭性甲狀旁腺激素 (PTH) 拮抗劑,在牛腎皮質膜中的 Ki 值為 69 nM。(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) 可用于生長發(fā)育調節(jié)。
靶點

Ki: 69 nM (PTH)

體外研究

(D-Trp12,Tyr34)-pTH (7-34) amide (0.05-10 μM) causes a concentration-dependent inhibition of PTHrP or PTH-stimulated cAMP formation in opossum kidney (OK) cells.
(D-Trp12,Tyr34)-pTH (7-34) amide (0.1-10 μM) attenuates inhibition of Nap i T promoted by 1 nM of either PTHrP or PTH.

體內研究

(D-Trp12,Tyr34)-pTH (7-34) amide (1 mg/mL once, 0.1 mg/mL for 6 h; i.v.) has no significant effect on serum calcium levels in hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung.

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