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10030-73-6

中文名稱 (9E)-9-十六烯酸
英文名稱 PALMITELAIDIC ACID
CAS 10030-73-6
分子式 C16H30O2
分子量 254.41
MOL 文件 10030-73-6.mol
10030-73-6 結(jié)構(gòu)式 10030-73-6 結(jié)構(gòu)式

基本信息

中文別名
棕櫚酸酯?
反式-棕櫚油酸
十六碳烯酸(反-9)
反式-9-十六碳烯酸
(9E)-9-十六烯酸
英文別名
PALMITELAIDIC ACID
C16:1 (TRANS-9) ACID
(e)-9-hexadecenoicaci
(E)-9-Hexadecenoicacid
PALMITELAIDIC ACID 99%
trans-palmitoleic acid
(9E)-9-Hexadecenoicacid
(9E)-Hexadec-9-enoic acid
TRANS-9-HEXADECENOIC ACID
9-trans-Hexadecenoic acid

物理化學(xué)性質(zhì)

熔點33-34℃
沸點374.4°C (estimate)
密度0.8855 (rough estimate)
折射率1.4501 (589.3 nm 40℃)
儲存條件Amber Vial, Refrigerator
溶解度可溶于DMSO(少量)、甲醇(少量)
酸度系數(shù)(pKa)4.78±0.10(Predicted)
形態(tài)液體
顏色白色至灰白色
LogP6.635 (est)
EPA化學(xué)物質(zhì)信息9-Hexadecenoic acid, (9E)- (10030-73-6)
(9E)-9-十六烯酸價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2025/02/08HY-N2341(9E)-9-十六烯酸
Palmitelaidic Acid
10030-73-610mg(393mM * 100μL in Ethanol)500元
2025/02/08HY-N2341(9E)-9-十六烯酸
Palmitelaidic Acid
10030-73-625 mg (393 mM * 250 μL in Ethanol)1000元
2025/02/08HY-N2341(9E)-9-十六烯酸
Palmitelaidic Acid
10030-73-650 mg (393 mM * 500 μL in Ethanol)1600元

常見問題列表

生物活性
Palmitelaidic Acid (9-trans-Hexadecenoic acid) 是棕櫚油酸 palmitoleic acid 的反式異構(gòu)體。 棕櫚油酸是血清和組織中最豐富的脂肪酸之一。
靶點

AMPK

PPARα

Glucokinase

體外研究

The monounsaturated fatty acid palmitoleate (palmitoleic acid) is one of the most abundant fatty acids in serum and tissues, particularly adipose tissue and liver. Its endogenous production by stearoyl-CoA desaturase 1 gives rise to its cis isoform, cis-palmitoleate. Palmitoleic acid has been correlated with multiple cardiometabolic risk factors, including high blood pressure, total cholesterol, TGs, apoA-I, apoB, and endothelial dysfunction.

體內(nèi)研究

Palmitoleic acid promotes a faster uptake of glucose in the body, associated with higher insulin concentration. Palmitoleic acid increases the phosphorylation of AMPK, up-regulates glucokinase and down-regulates SREBP-1. Regarding AMPK downstream, palmitoleic acid increases the production of FGF-21 and stimulates the expression of PPARα. Palmitoleic acid reduces body weight increase, ameliorates the development of hyperglycemia and hypertriglyceridemia, and improves insulin sensitivity. Furthermore, palmitoleic acid down-regulates mRNA expressions of proinflammatory adipocytokine genes (TNFα and resistin) in white adipose tissue and lipogenic genes (SREBP-1, FAS, and SCD-1) in liver.

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