| Identification | More | [Name]
2-Hydroxybenzyl alcohol | [CAS]
90-01-7 | [Synonyms]
2-HYDROXYBENZYL ALCOHOL
2-METHYLOLPHENOL
HYDROXYBENZYL-2 ALCOHOL
O-HYDROXYBENZYL ALCOHOL
O-(HYDROXYMETHYL)PHENOL
RARECHEM AL BD 0029
SALICAIN
SALICYL ALCOHOL
SALIGENIN
SALIGENINE
SALIGENOL
,2-Dihydroxytoluene
2-hydroxy-benzenemethano
2-Hydroxybenzenemethanol
2-hydroxy-Benzenemethanol
2-Hydroxymethylphenol
alpha,2-Dihydroxytoluene
alpha-Hydroxy-o-cresol
Benzenemethanol, 2-hydroxy-
Benzyl alcohol, o-hydroxy- | [EINECS(EC#)]
201-960-5 | [Molecular Formula]
C7H8O2 | [MDL Number]
MFCD00004617 | [Molecular Weight]
124.14 | [MOL File]
90-01-7.mol |
| Chemical Properties | Back Directory | [Appearance]
light brown crystalline powder | [Melting point ]
83-85 °C(lit.)
| [Boiling point ]
190.92°C (rough estimate) | [density ]
1,613 g/cm3 | [refractive index ]
1.5035 (estimate) | [storage temp. ]
Store below +30°C. | [solubility ]
ethanol: soluble5%, clear to very slightly hazy, colorless to light yellow | [form ]
Crystalline Flakes or Powder | [pka]
pK1:9.92 (25°C) | [color ]
Light beige | [Stability:]
Stable. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents. | [Water Solubility ]
67 g/L (22 ºC) | [Merck ]
14,8325 | [BRN ]
1907195 | [Contact allergens]
Methylol phenols are sensitizers contained in resins
based on phenol and formaldehyde of the resol type.
Cross-reactivity is possible with other phenol derivative
molecules. | [LogP]
0.730 | [CAS DataBase Reference]
90-01-7(CAS DataBase Reference) | [NIST Chemistry Reference]
Salicyl alcohol(90-01-7) | [EPA Substance Registry System]
90-01-7(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
light brown crystalline powder | [Uses]
2-Hydroxybenzyl Alcohol is a phenolic component of a part of a salix bark extract which maintains a minor anti-depressant effect. Phenolic analog with potential for anti-melanomic effect | [Uses]
anesthetic (local), antiinflammatory | [Definition]
ChEBI: A hydroxybenzyl alcohol that is phenol substituted by a hydroxymethyl group at C-2. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 60, p. 5314, 1995 DOI: 10.1021/jo00121a060
Tetrahedron Letters, 10, p. 1739, 1969 | [General Description]
2-Hydroxybenzyl alcohol participates in the selective ring opening reaction of 4H-1,3,2-benzodioxasilines. | [Purification Methods]
Crystallise saligenine from water or EtOH/*C6H6 (m 89o). [Beilstein 6 III 4537, 6 IV 5896.] |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
DO6430000
| [TSCA ]
Yes | [HS Code ]
29072900 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Formaldehyde | [Preparation Products]
Xanthene-->SALITHION-->2-DIMETHYLAMINOMETHYLPHENOL (CONTAINS PHENOL)-->2,2'-METHYLENEDIPHENOL-->2-SALICYLIDENEAMINOPHENOL-->5-(CHLOROMETHYL)-2-HYDROXYBENZALDEHYDE-->N,N'-DISALICYLAL-1,2-PHENYLENEDIAMINE-->SALICYLIDENEANILINE-->2,4,4,6-TETRABROMO-2,5-CYCLOHEXADIENONE-->4H-1,3-Benzodioxin, 2,2-dimethyl--->CHEMBRDG-BB 9070765-->2-(1H-IMIDAZOL-2-YLMETHYL)-PHENOL-->o-Hydroxybenzylchloride |
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