| Identification | More | [Name]
Enoximone | [CAS]
77671-31-9 | [Synonyms]
1,3-DIHYDRO-4-METHYL-5-[4-METHYLTHIOBENZOYL]-2H-IMIDAZOL-2-ONE
ENOXIMONE
2H-Imidazol-2-one, 1,3-dihydro-4-methyl-5-(4-(methylthio)benzoyl)-
Fenoximone
MDL-17043
Pedane
Perfan
RMI-17043 | [Molecular Formula]
C12H12N2O2S | [MDL Number]
MFCD00867130 | [Molecular Weight]
248.3 | [MOL File]
77671-31-9.mol |
| Hazard Information | Back Directory | [Description]
Enoximone is a phosphodiesterase inhibitor indicated for selective use as a
cardiostimulant in heart transplant patient maintenance. It is currently being investigated
for other indications including acute congestive heart failure. | [Originator]
Merrell Dow (USA) | [Uses]
Enoximone is a phosphodiesterase inhibitor used in the treatment of congestive heart failure and is selective to phosphodiesterase 3. Potent PDE-3 inhibitor. | [Definition]
ChEBI: Enoximone is an aromatic ketone. | [Brand name]
Perfan IV | [Biological Activity]
Inhibitor of type III phosphodiesterase (PDE3). Increases intracellular cyclic AMP (cAMP) concentrations and enhances myocardial contractility. Also induces concentration-dependent vasodilation in vitro . | [Biochem/physiol Actions]
Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart. | [storage]
Store at -20°C |
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| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
TCI Europe
|
| Tel: |
320-37350700 |
| Website: |
https://www.tcichemicals.com/de/de/index.html |
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