Identification | More | [Name]
5,7-Dichloro-8-hydroxyquinoline | [CAS]
773-76-2 | [Synonyms]
5,7-DICHLORO-8-HYDROXYQUINOLINE 5,7-DICHLORO-8-OXINE 5,7-DICHLORO-8-QUINOLINOL AKOS BBS-00002684 CHLOROXINE 5,7-Dichlor-8-hydroxychinolin 5,7-Dichloro-8-hydroquinoline 5,7-Dichloro-8-hydroxyquinolin 5,7-Dichloro-8-oxychinolin 5,7-Dichloro-8-oxyquinoline 5,7-dichloro-8-quinolino 5,7-Dichlorooxine 5,7-Dichloroxine 8-Quinolinol,5,7-dichloro- Capitrol Chhoroox-ine Chlofucid CHQ Clofuzid component of Capitrol Cream Shampoo | [EINECS(EC#)]
212-258-3 | [Molecular Formula]
C9H5Cl2NO | [MDL Number]
MFCD00006786 | [Molecular Weight]
214.05 | [MOL File]
773-76-2.mol |
Chemical Properties | Back Directory | [Appearance]
light beige fluffy powder | [Melting point ]
178-180 °C (lit.) | [Boiling point ]
305.47°C (rough estimate) | [density ]
1.3320 (rough estimate) | [refractive index ]
1.5500 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated, Sonicated) | [form ]
Fluffy Powder | [pka]
2.30±0.30(Predicted) | [color ]
Light beige | [Merck ]
14,2175 | [BRN ]
153606 | [Stability:]
Light Sensitive | [CAS DataBase Reference]
773-76-2(CAS DataBase Reference) | [NIST Chemistry Reference]
8-Quinolinol, 5,7-dichloro-(773-76-2) | [EPA Substance Registry System]
773-76-2(EPA Substance) |
Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed. R37/38:Irritating to respiratory system and skin . R41:Risk of serious damage to eyes. R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S37/39:Wear suitable gloves and eye/face protection . S25:Avoid contact with eyes . S22:Do not breathe dust . | [WGK Germany ]
3
| [RTECS ]
VC5350000
| [TSCA ]
Yes | [HS Code ]
29334900 |
Hazard Information | Back Directory | [Chemical Properties]
light beige fluffy powder | [Uses]
Analytical reagent. | [Uses]
Chloroxine, is an impurity of Cioquinol, which is an antifungal and antiprotozoal drug. | [Uses]
H1 antihistamine | [Definition]
ChEBI: Quinolin-8-ol in which the hydrogens at positions 5 and 7 have been substituted by chlorine. An synthetic antibacterial prepared by chlorination of quinolin-8-ol, it is used for the treatment of dandruff and seborrhoeic dermatitis of the scalp. | [Indications]
Chloroxine (Capitrol) shampoo contains a synthetic antibacterial compound
similar to the hydroxyquinoline compounds used in dermatology for many
years. | [Brand name]
Capitrol (Westwood-
Squibb). | [Purification Methods]
Crystallise the dichloro-oxine from acetone/EtOH. [Beilstein 21 H 95.] |
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