| Identification | More | [Name]
Dithioerythritol | [CAS]
6892-68-8 | [Synonyms]
1,4-DIMERCAPTO-2,3-BUTANEDIOL
1,4-DITHIOERYTHRITOL
2,3-DIHYDROXY-1,4-BUTANEDITHIOL
CLELAND REAGENT
CLELAND'S OTHER REAGENT
CLELANDS REAGENT
CLELAND'S REAGENT
DITHIOERYTHREITOL
DITHIOERYTHRITOL
DL-DITHIOERYTHRITOL
DTE
ERYTHRO-1,4-DIMERCAPTO-2,3-BUTANEDIOL
ERYTHRO-2,3-DIHYDROXY-1,4-BUTANEDITHIOL
ERYTHRO-2,3-DIHYDROXY-1,4-DITHIOLBUTANE
(S,R)-DITHIOERYTHRITOL
(r*,s*)-1,4-dimercapto-2,3-butanediol
1,4-dimercapto-,(r*,s*)-3-butanediol
1,4-dimercapto-,(theta,s)-3-butanediol
1,4-dithio-erythrito
3-Butanediol,1,4-dimercapto-,(R*,S*)-2 | [EINECS(EC#)]
229-998-8 | [Molecular Formula]
C4H10O2S2 | [MDL Number]
MFCD00063750 | [Molecular Weight]
154.25 | [MOL File]
6892-68-8.mol |
| Chemical Properties | Back Directory | [Appearance]
White solid | [Melting point ]
82-84 °C(lit.) | [Boiling point ]
247.65°C (rough estimate) | [density ]
1.156 (estimate) | [refractive index ]
1.5200 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
H2O: 10 mg/mL, clear, colorless
| [form ]
Powder | [pka]
pK1:9.5 (25°C) | [color ]
White to pale yellow or beige | [PH]
4.0-6.0 (25℃, 0.1M in H2O) | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents. | [Water Solubility ]
Soluble | [Sensitive ]
Air Sensitive | [λmax]
λ: 260 nm Amax: 0.400
λ: 280 nm Amax: 0.050 | [BRN ]
1719756 | [InChIKey]
VHJLVAABSRFDPM-ZXZARUISSA-N | [CAS DataBase Reference]
6892-68-8(CAS DataBase Reference) | [EPA Substance Registry System]
6892-68-8(EPA Substance) | [Absorption]
≤0.4 at 280 in H2O at 0.1M
≤0.6 at 260 in H2O at 0.1M |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
UN 3335 | [WGK Germany ]
3
| [RTECS ]
KF2410000
| [F ]
3-10-13-23 | [TSCA ]
Yes | [HazardClass ]
9 | [HS Code ]
29309099 |
| Hazard Information | Back Directory | [Chemical Properties]
White solid | [Uses]
Reagent for maintaining ?SH groups in the reduced state; quantitatively reduces disulfides. | [Uses]
1,4-Dithioerythritol is a Michael reaction acceptor; inducers of enzymes that protect against carcinogenesis: reactivity with sulfhydryl groups. | [Uses]
Reagent for the reduction of disulfide group. Prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis. Cleavage of disulfide bonds in proteins | [Definition]
ChEBI: The meso-diastereomer of 1,4-dimercaptobutane-2,3-diol; a sulfur-containing sugar derived from the monosaccharide erythrose; and an epimer of dithiothreitol. | [reaction suitability]
reagent type: reductant | [Purification Methods]
Crystallise DTE from ether/hexane and store it in the dark at 0o. [Beilstein 1 III 2360.] |
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