Identification | More | [Name]
4-CHLORO-2-PHENYLQUINAZOLINE | [CAS]
6484-25-9 | [Synonyms]
4-CHLORO-2-PHENYLQUINAZOLINE AKOS 93518 AM-EX-OL(R) QUINAZOLINE, 4-CHLORO-2-PHENYL- 4-CHLORO-2-PHENYLQUINAZOLINE
OR
AM-ex-OL AM-EX-OL, 97% (4-CHLORO-2-PHENYL-QUINAZO LINE) am-ex-ol tm 4-CHLORO-2-PHENYLQUINAZOLINE 97% 4-CHLORO-2-PHENYLQUINAZOLINE HPLC 99+% 2-Phenyl-4-chloroquinazoline | [EINECS(EC#)]
229-346-2 | [Molecular Formula]
C14H9ClN2 | [MDL Number]
MFCD00006713 | [Molecular Weight]
240.69 | [MOL File]
6484-25-9.mol |
Chemical Properties | Back Directory | [Appearance]
slightly yellow to yellow crystalline powder | [Melting point ]
124-126 °C(lit.) | [Boiling point ]
383.11°C (rough estimate) | [density ]
1.285 | [refractive index ]
1.5749 (estimate) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [form ]
Crystalline Powder | [pka]
0.67±0.30(Predicted) | [color ]
Slightly yellow to yellow | [InChIKey]
OBHKONRNYCDRKM-UHFFFAOYSA-N | [CAS DataBase Reference]
6484-25-9(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HS Code ]
29339980 |
Hazard Information | Back Directory | [Chemical Properties]
slightly yellow to yellow crystalline powder | [Uses]
Reactant involved in the synthesis of biologically active molecules including:
- Nitrotriazole amines or nitroimidazole amines for use as antitrypanosomal activity and mammalian cytotoxicity
- Quinazoline-containing piperazinylpyrimidine derivatives with antitumor activity
- Quinazoline substituted cyclopentane as HCV NS3/4A protease inhibitors
- Quinazolines with antibacterial and antitumor activity
- Aurora inhibitor MK-0457
Reactant involved in Suzuki-Miyaura cross-coupling and catalyst-free / base-free water promoted nucleophilic aromatic substitution | [Uses]
4-Chloro-2-phenylquinazoline can be involved in the synthesis of biologically active molecules including: Nitrotriazole amines or nitroimidazole amines for use as antitrypanosomal activity and mammalian cytotoxicity.
| [Synthesis Reference(s)]
Journal of the American Chemical Society, 68, p. 1299, 1946 DOI: 10.1021/ja01211a055 |
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