Identification | More | [Name]
Nimustine hydrochloride | [CAS]
55661-38-6 | [Synonyms]
1-(4-AMINO-2-METHYL-5-PYRIMIDINYL)-METHYL-3-(2-CHLOROETHYL)-3-NITROSOUREA HYDROCHLORIDE ACNU N'-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-N-(2-CHLOROETHYL)-N-NITROSOUREA HYDROCHLORIDE NIMUSTINE HCL NIMUSTINE HYDROCHLORIDE 1-(2-cloroetil)-1-nitroso-3-((2-metil-4-aminopirimidin-5-il)metil)ureaclorhi 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosoureahydr 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitroso-ure 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitrosoureah cs-439 n’-((4-amino-2-methyl-5-pyrimidinyl)methyl)-n-(2-chloroethyl)-n-nitrosourea n’-((4-amino-2-metil-5-pirimidinil)metil)-n-(2-cloroetil)-n-nitrosoureaclorh nidran nimustinaclorhidrato nsc-245,382 1-((4-Amino-2-methylpyrimidin-5-yl)methyl)-3-(2-chloroethyl)-3-nitrosourea hydrochloride 3-[(4-Amino-2-methyl-pyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitroso-urea hydrochloride NSC-D-245382 | [EINECS(EC#)]
678-313-2 | [Molecular Formula]
C9H14Cl2N6O2 | [MDL Number]
MFCD01676942 | [Molecular Weight]
309.15 | [MOL File]
55661-38-6.mol |
Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R25:Toxic if swallowed. | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 | [RTECS ]
YR8450000 | [HS Code ]
2933.59.8000 | [HazardClass ]
6.1 | [PackingGroup ]
III | [Toxicity]
LD50 in mice, rats (mg/kg): 62, 46 i.v. (Masuda) |
Hazard Information | Back Directory | [Uses]
Nimustine Hydrochloride is a DNA alkylator and cross-linking agent. It is used in chemotherapy in a part of anti-cancer cocktail used to treat malignant melanoma. | [Definition]
ChEBI: A hydrochloride obtained by combining nimustine with one equivalent of hydrochloric acid. An antineoplastic agent especially effective against malignant brain tumors. | [storage]
4°C, protect from light |
|
|