| Identification | Back Directory | [Name]
SULOCHRIN | [CAS]
519-57-3 | [Synonyms]
2,4',6-Trihydroxy-4-methyl-2'-(methoxycarbonyl)-6'-methoxybenzophenone
2-(2,6-Dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoic acid methyl ester
Benzoic acid, 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxy-, methyl ester | [Molecular Formula]
C17H16O7 | [MDL Number]
MFCD07370145 | [MOL File]
519-57-3.mol | [Molecular Weight]
332.3 |
| Chemical Properties | Back Directory | [Melting point ]
242-248 °C (decomp) | [Boiling point ]
576.3±50.0 °C(Predicted) | [density ]
1.378±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMF: soluble | [form ]
solid | [pka]
6.55±0.25(Predicted) |
| Hazard Information | Back Directory | [Uses]
Sulochrin is a fungal metabolite isolated from a number of Aspergillus and Penicillium sp.. An anti-angiogenic agent, sulochrin inhibits VEGF leading to inhibition of capillary-like tube formation of human umbilical vein endothelial cells. Sulochrin also inhibits eosinophil activation and chemotaxis. | [Uses]
Sulochrin is an inhibitor of the degranulation, activation and chemotaxis of eosinophils. | [Definition]
ChEBI: Sulochrin is a benzophenone that is the methyl ester of 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoic acid. It has a role as a metabolite. It is a member of benzophenones, a carboxylic ester and a member of phenols. It is functionally related to a demethylsulochrin. It is a conjugate acid of a sulochrin(1-). | [storage]
Store at -20°C |
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