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ChemicalBook--->CAS DataBase List--->31137-74-3

31137-74-3

31137-74-3 Structure

31137-74-3 Structure
IdentificationMore
[Name]

(2S,4R)-4-METHYLGLUTAMIC ACID
[CAS]

31137-74-3
[Synonyms]

SYM 2081
(2S,4R)-4-MethylglutamicAci
(2S-R)-4-METHYLGLUTAMIC ACID
(2S,4R)-4-METHYLGLUTAMIC ACID
(4R)- 4-Methyl-L-glutamic Acid
L-erythro--Methylglutamic Acid
erythro-L-4-Methylglutamic Acid
ERYTHRO-4-METHYL-L-GLUTAMIC ACID
L-Glutamic acid, 4-methyl-, (4R)-
(2S,4R)-4-METHYLGLUTAMIC ACID USP/EP/BP
(2S,4R)-(+)-2-Amino-4-methylpentanedioic acid
(2S,4R)-(+)-2-AMINO-4-METHYLPENTANEDIOIC ACID 99%
(2S,4R)-(+)-2-Amino-4-methylpentanedioic acid,99%
[Molecular Formula]

C6H11NO4
[MDL Number]

MFCD00937765
[Molecular Weight]

161.16
[MOL File]

31137-74-3.mol
Chemical PropertiesBack Directory
[Appearance]

White
[Melting point ]

178 °C
[Boiling point ]

287.44°C (rough estimate)
[density ]

1.3482 (rough estimate)
[refractive index ]

1.4230 (estimate)
[storage temp. ]

Store at RT
[solubility ]

H2O: >10 mg/mL
[form ]

solid
[pka]

2.34±0.21(Predicted)
[color ]

white
[Usage]

A highly selective and potent agonist for kainate receptors.
[CAS DataBase Reference]

31137-74-3(CAS DataBase Reference)
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Chemical Properties]

White
[Uses]

A highly selective and potent agonist for kainate receptors.
[Biological Activity]

Potent and highly selective kainate receptor agonist, with an IC 50 for inhibition of [ 3 H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. Also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™ and Kainate Receptor Tocriset™ .
[IC 50]

Kainate Receptor
[storage]

Store at RT
Spectrum DetailBack Directory
[Spectrum Detail]

(2S,4R)-4-METHYLGLUTAMIC ACID(31137-74-3)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

31137-74-3(sigmaaldrich)
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