午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

ChemicalBook--->CAS DataBase List--->168835-82-3

168835-82-3

168835-82-3 Structure

168835-82-3 Structure
IdentificationBack Directory
[Name]

(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
[CAS]

168835-82-3
[Synonyms]

CS-1481
CHEMBL261508
SU1498, >98%
Tyrphostin SU 1498, >98%
(E)-2-CYANO-3-(4-HYDROXY-3
AG-1498;TYRPHOSTIN SU 1498
5-DIISOPROPYLPHENYL)-N-(3-PHENYLPROPYL)ACRYLAMIDE
(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropy
(E)-2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
2-Propenamide, 2-cyano-3-[4-hydroxy-3,5-bis(1-methylethyl)phenyl]-N-(3-phenylpropyl)-, (2E)-
SU1498; TYRPHOSTIN SU 1498; CHEMBL261508; (E)-2-CYANO-3-(4-HYDROXY-3;5-DIISOPROPYLPHENYL)-N-(3-PHENYLPROPYL)ACRYLAMIDE
Vascular endothelial growth factor receptor,Inhibitor,Su-1498,AG1498,AG-1498,Su1498,Tyrphostin SU1498,inhibit,Tyrphostin SU-1498,VEGFR,SU 1498
[Molecular Formula]

C25H30N2O2
[MDL Number]

MFCD03453026
[MOL File]

168835-82-3.mol
[Molecular Weight]

390.518
Chemical PropertiesBack Directory
[Melting point ]

126 °C
[Boiling point ]

590.6±50.0 °C(Predicted)
[density ]

1.100±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Soluble in DMSO.
[form ]

powder
[pka]

10.30±0.36(Predicted)
[color ]

white to beige
[Stability:]

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
[CAS DataBase Reference]

168835-82-3
Safety DataBack Directory
[HS Code ]

2926.90.4801
Hazard InformationBack Directory
[Description]

SU-1498 (168835-82-3) is a potent, reversible, selective inhibitor of VEGFR-2, also known as Flk-1 (IC50 = 700 nM). Inhibition of VEGFR-2 blocks angiogenesis in both in vitro and in vivo models. Cell permeable.
[Uses]

SU 1498 is an inhibitor of VEGF receptor kinase.
[Definition]

ChEBI: SU1498 is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2E)-2-cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enoic acid with the amino group of 3-phenylpropylamine. It has a role as a vascular endothelial growth factor receptor antagonist. It is an enamide, a member of phenols, a nitrile, a monocarboxylic acid amide and a secondary carboxamide.
[Biochem/physiol Actions]

SU1498 is a potent and selective inhibitor of the VEGFR2 receptor kinase, Flk-1 with an IC50 value of 700 nM. SU1498 is a very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase with IC50 values > 50 μM. SU1498 has been used to study the role of VEGFR2 (Flk-1) in a variety of biological activities including angiogenesis, tumor growth inhibition, and stem cell proliferation.
[storage]

Store at -20°C
[References]

1) Cho et al. (2005), Retinoic acid and erythropoietin maintain alveolar development in mice treated with an angiogenesis inhibitor; Am. J. Respir. Cell Mol. Biol., 33 622 2) Wang et al. (2002), Interplay between integrins and FLK-1 in shear stress-induced signaling; Am. J. Physiol. Cell Physiol., 283 C1540 3) Strawn et al. (1996), FLK-1 as a target for tumor growth inhibition; Cancer Res., 56 3540
168835-82-3 suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Website: www.atkchemical.com
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: TargetMol Chemicals Inc.
Tel:
Website: www.targetmol.com/
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel: 13417589054 , 13417589054
Website: www.yuhua99.com/ShowSupplierProductsList1962465/0.htm
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Website: www.aladdinsci.com/
Company Name: Adamas Reagent, Ltd.  
Tel: 400-6009262 16621234537
Website: http://www.tansoole.com
Company Name: TOKYO CHEMICAL INDUSTRY CO., LTD.  
Tel: 03-36680489
Website: https://www.tcichemicals.com/ja/jp/index.html
Company Name: MedChemexpress LLC  
Tel: 021-58955995
Website: www.medchemexpress.cn
Company Name: Shanghai JiYi Biotechnology Co. Ltd.  
Tel: 13621943973
Website: www.yuhua99.com/ShowSupplierProductsList16460/0.htm
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Website: https://www.sigmaaldrich.cn
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Website: http://www.cw-bio.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: 021-QQ:65489617 15618227136
Website: www.atkchemical.com/
Company Name: Medi-tech Bioscientific Co., Ltd.  
Tel: 0519-83246372 13585352506
Website: www.yuhua99.com/ShowSupplierProductsList19938/0.htm
Company Name: Angel Pharmatech, Ltd.  
Tel: 17317130613
Website: http://www.angelpharmatech.com
Company Name: TCI Chemicals  
Tel: 021-67121386, 800-988-0390
Website: www.tcichemicals.com
Company Name: BOC Sciences  
Tel:
Website: https://www.bocsci.com
Company Name: DC Chemicals  
Tel: 021-58447131 13564518121
Website: http://www.yuhua99.com/ShowSupplierProductsList927327/0.htm
Tags:168835-82-3 Related Product Information
186610-88-8 186611-11-0 627908-92-3 186610-89-9 215543-92-3 179324-69-7 341031-54-7 520-36-5 915019-65-7 186611-04-1 186611-55-2 704869-38-5 76086-99-2 658084-23-2 3476-86-6 5812-07-7 9026-00-0 75-04-7

This site uses cookies
This website uses cookies and similar technologies to store and retrieve information about your use of this website. This information helps us to provide, analyse and improve our services, which may include personalised content or advertising. We may share this information with Google and other third parties. This cookies are necessary for our website to work properly . By clicking "Continue" or continuing to browse our site you are agreeing to our and our partners use of cookies.
Accept