| Identification | Back Directory | [Name]
Kazinol U | [CAS]
1238116-48-7 | [Synonyms]
Kazinol U
4-[(2R)-3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-1,2-benzenediol
1,2-Benzenediol, 4-[(2S)-3,4-dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)- | [Molecular Formula]
C20H22O4 | [MOL File]
1238116-48-7.mol | [Molecular Weight]
326.39 |
| Chemical Properties | Back Directory | [Boiling point ]
538.8±50.0 °C(Predicted) | [density ]
1.243±0.06 g/cm3(Predicted) | [storage temp. ]
-10 to -25°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
9.72±0.40(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Biological Activity]
Kazinol U is prenylated flavan isolated from an extract of Broussonetia kazinoki Sieb (paper mulberry) th at exhibits anti-melanogenic activity in mouse and human melanoma cells through the induction of AMPK and MAPK phosphorylation. Kazinol U inhibits tyrosinase activity and melanin synthesis through the reduction of MITF expression. It suppresses melanogenesis in a zebrafish model. Kazinol U displays phytoestrogenic and anti-inflammatory activities. Kazinol U exhibits cytoprotective activities against cytokine-induced apoptotic cell death. | [target]
Estrogen receptor | NF-kB | IkB | NO | NOS | IFN-γ | IL Receptor | IKK | Progestogen receptor |
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| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
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