| Identification | More | [Name]
Dimethyl succinate | [CAS]
106-65-0 | [Synonyms]
AKOS BBS-00004425
BUTANEDIOIC ACID DIMETHYL ESTER
DBE-4 DIBASIC ESTER
DIBASIC ESTER
DIBASIC ESTER (ESTASOL(R))
DIMETHYL BUTANEDIOATE
DIMETHYL SUCCINATE
DMS
ESTASOL(R)
FEMA 2396
methyl butanedioate
METHYL SUCCINATE
SUCCINIC ACID BIS-METHYL ESTER
SUCCINIC ACID DIMETHYL ESTER
1,4-butanedioicacid,dimethylester
CH3OC(O)CH2CH2C(O)OCH3
DBE-4
Dimethyl ester of succinic acid
dimethyl1,4-butanedioate
DIMETHYLE SUCCINATE | [EINECS(EC#)]
203-419-9 | [Molecular Formula]
C6H10O4 | [MDL Number]
MFCD00008466 | [Molecular Weight]
146.14 | [MOL File]
106-65-0.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless liquid | [Melting point ]
16-19 °C (lit.) | [Boiling point ]
200 °C (lit.) | [density ]
1.117 g/mL at 25 °C(lit.)
| [vapor pressure ]
0.3 mm Hg ( 20 °C)
| [FEMA ]
2396 | [refractive index ]
n20/D 1.419(lit.)
| [Fp ]
185 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
75g/l | [form ]
Liquid | [color ]
Clear | [Odor]
Fruity | [Stability:]
Stable. Combustible. Incompatible with oxidizing agents, acids, bases, reducing agents. | [explosive limit]
1.0-8.5%(V) | [Odor Type]
fruity | [Water Solubility ]
8.5 g/L (20 ºC) | [JECFA Number]
616 | [Merck ]
14,8869 | [BRN ]
956776 | [Dielectric constant]
5.1（20℃） | [LogP]
0.33 at 40℃ | [CAS DataBase Reference]
106-65-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Butanedioic acid, dimethyl ester(106-65-0) | [EPA Substance Registry System]
106-65-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36:Irritating to the eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN 1993 | [WGK Germany ]
1
| [RTECS ]
WM7675000
| [Autoignition Temperature]
689 °F | [TSCA ]
Yes | [HS Code ]
29171990 | [Hazardous Substances Data]
106-65-0(Hazardous Substances Data) |
| Hazard Information | Back Directory | [General Description]
Colorless liquid. | [Reactivity Profile]
DIMETHYL SUCCINATE(106-65-0) reacts with acids to liberate heat along with methanol and succinic acid. May react with strong oxidizing acids to liberate enough heat to ignite the reaction products. Heat is also generated by the interaction with caustic solutions. Flammable hydrogen is generated with alkali metals and hydrides. | [Air & Water Reactions]
Water soluble. | [Health Hazard]
May be harmful by inhalation, ingestion or skin absorption. May cause irritation. | [Fire Hazard]
This chemical is combustible. Vapor forms explosive mixtures with air. | [Chemical Properties]
colourless liquid | [Chemical Properties]
Dimethyl succinate has a pleasant, ethereal, winy odor and fruity, winy and burning flavor | [Occurrence]
Reported found in filbert nuts and starfruit. | [Uses]
Dimethyl succinate is used as a flavoring agent. It have wide range of industrial applications such as Functional fluids (open systems), Intermediates, Paint additives and coating additives, Pigments Solvents, Viscosity adjustors. | [Definition]
ChEBI: Dimethyl succinate is a fatty acid methyl ester. | [Preparation]
By direct esterification of the acid with the alcohol in benzene solution at the boil in the presence of concentrated H2SO4 | [Taste threshold values]
Taste characteristics at 0.1%: sweet, fruity, green with a soapy, waxy nuance | [Synthesis Reference(s)]
Journal of the American Chemical Society, 100, p. 1119, 1978 DOI: 10.1021/ja00472a016
The Journal of Organic Chemistry, 59, p. 3500, 1994 DOI: 10.1021/jo00091a050 | [Toxics Screening Level]
All
screening levels for DBE, including the new ITSL of 1 μg/m3 (annual) are based on a 90-day
inhalation study Keenan et a/.(1990), which identified a lowest-observed-adverse-effect-level
(LOAEL) of 20 mg/m3 for degeneration of nasal epithelium in female rats. Up to this time, the
individual dimethyl esters each had ITSLs of 0.1 μg/m3 (annual). |
| Questions And Answer | Back Directory | [Description]
Dimethyl succinate belong to the diester of methyl alcohol and succinic acid, which can be found in nuts. It is a biodegradable ester with low odor and low volatility and commonly serves as a flavoring agent that can be used in perfumery and personal are products, including skin-conditioning agents and emollient. It also has a variety of industrial usages such as functional fluids (open systems), intermediates, paint additives and coating additives, pigments, viscosity adjustors, etc. Besides, dimethyl succinate can be used in the production of pharmaceuticals as well as agrochemicals and for manufacturing additives, plastics and other organic compounds. In spite of its slightly water-soluble property, it can also act as a surfactant applied in water based systems.
| [References]
http://www.chemicalland21.com/specialtychem/perchem/DIMETHYL%20SUCCINATE.htm
https://www.ewg.org/skindeep/ingredient/702064/DIMETHYL_SUCCINATE/
https://www.alfa.com/zh-cn/catalog/A12565/
https://pubchem.ncbi.nlm.nih.gov/compound/7820#section=Consumer-Uses
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