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ChemicalBook CAS DataBase List Ramosetron hydrochloride
132907-72-3

Ramosetron hydrochloride synthesis

2synthesis methods
132036-88-5 Synthesis
RAMOSETRON

132036-88-5
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$35.00/10mg

Methanone, (1-methyl-1H-indol-6-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)-

912850-42-1
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Methanone, (1-methyl-1H-indol-5-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)-

912850-41-0
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Yield:99.2 - 99.5 % ee

Reaction Conditions:

with hydrogenchloride in ethanol;ethyl acetate at 70; for 1 - 12 h;Product distribution / selectivity;

References:

WO2006/109762,2006,A1 Location in patent:Page/Page column 10-11

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