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ChemicalBook CAS DataBase List (R)(-)-2-BENZYLAMINO-1-BUTANOL
6257-49-4

(R)(-)-2-BENZYLAMINO-1-BUTANOL synthesis

10synthesis methods
-

Yield:6257-49-4 97%

Reaction Conditions:

Stage #1: (2R)-2-aminobutan-1-ol;benzaldehyde in methanol at 20; for 1 h;Inert atmosphere;
Stage #2: with sodium tetrahydroborate in methanol at 0 - 20; for 1.5 h;Inert atmosphere;

References:

Hillisch, Alexander;Gericke, Kersten M.;Allerheiligen, Swen;Roehrig, Susanne;Schaefer, Martina;Tersteegen, Adrian;Schulz, Simone;Lienau, Philip;Gnoth, Mark;Puetter, Vera;Hillig, Roman C.;Heitmeier, Stefan [Journal of Medicinal Chemistry,2020,vol. 63,# 21,p. 12574 - 12594] Location in patent:supporting information

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