Protoporphyrin IX dimethyl ester synthesis
- Product Name:Protoporphyrin IX dimethyl ester
- CAS Number:5522-66-7
- Molecular formula:C36H38N4O4
- Molecular Weight:590.71
553-12-8
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$39.20/100MG
5522-66-7
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$65.00/100mg
Yield:5522-66-7 79%
Reaction Conditions:
with sulfuric acid in methanol for 12 h;Darkness;
Steps:
3.1. Chlorin derivatives syntheses
The preparation of protoporphyrin IX dimethyl ester (PpIX) (7),described in Scheme 1, began with a process of elimination of twohydroxyl (-OH) groups of hematoporphyrin (Hp) (6). Then, anesterification in the presence of methanol and sulfuric acid (H2SO4)(5%)was performed maintaining the protection fromlight. The finalproduct 7 was obtained after solvent evaporation and a simplecrystallization from CHCl3:MeOH (1:3). Compound 7 was isolatedin 79% yield and characterised by 1H NMR and UV-Vis in order toconfirm its identity and purity.
References:
Linares, Irwin A.P.;de Oliveira, Kleber T.;Perussi, Janice Rodrigues [Dyes and Pigments,2017,vol. 145,p. 518 - 527]
67-56-1
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553-12-8
201 suppliers
$39.20/100MG
5522-66-7
121 suppliers
$65.00/100mg
67-56-1
751 suppliers
$7.29/5ml-f
50865-01-5
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5522-66-7
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$65.00/100mg
992-36-9
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5522-66-7
121 suppliers
$65.00/100mg
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5522-66-7
121 suppliers
$65.00/100mg