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ChemicalBook CAS DataBase List Palmityl myristate
2599-01-1

Palmityl myristate synthesis

3synthesis methods
-

Yield:-

Reaction Conditions:

with phosphoric acid in hexane;water for 8.5 h;Product distribution / selectivity;Heating / reflux;

Steps:

A
Experiment A.-Hexane Solvent; Myristic acid/palmitic acid, 200 cc. of 85% phosphoric acid and 1800 ml. of hexane were mixed, heated to reflux and then 251 grams of cetyl alcohol added in 30 min. The mixture was refluxed further for 8 hours. Then the hot mixture consisted of a muddy acid layer and a opaque solvent layer which could not be separated by decantation or filtration. The mixture was further diluted with three volumes of hexane causing the slushy hexane layer to further soften enough to be separated from aqueous layer. The hexane layer was then cooled to bring about crystallization of fatty ester. The weight of cetyl myristate isolated was 294 grams which had a melting point of 54-59° C. The conversion, based on the cetyl alcohol used, was 63.71%

References:

Cadwallader, Diane;Jhaveri, Parag US2005/33070, 2005, A1 Location in patent:Page/Page column 1

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