P-TOLYL DISULFIDE synthesis
- Product Name:P-TOLYL DISULFIDE
- CAS Number:103-19-5
- Molecular formula:C14H14S2
- Molecular Weight:246.39
1576-35-8
452 suppliers
$10.00/1g
103-19-5
158 suppliers
$19.00/5g
Yield:103-19-5 100%
Reaction Conditions:
with 1,10-Phenanthroline;oxygen;manganese triacetate;lithium bromide in dimethyl sulfoxide at 80; under 760.051 Torr; for 12 h;Green chemistry;chemoselective reaction;
Steps:
15 4.2 General procedure for the synthesis of C3-thioether indoles 3
General procedure: A mixture of alkynes 1 (0.5mmol), 2 (0.6mmol), Mn(OAc)3 (23mg, 20mol%), LiBr (10mol%), 1,10-phen (10mol%) in DMSO under 1atm oxygen atmosphere in a test tube (15mL) equipped with a magnetic stirring bar. The mixture was stirred at 80°C for given time. After the reaction was completed, 10mL ethyl acetate (3×10mL) was added into the tube. The combined organic layers were washed with brine to neutral, dried over MgSO4, and concentrated in vacuum. Purification of the residue on a preparative TLC afforded the desired products.
References:
He, Lin;Li, Xianwei [Tetrahedron,2017,vol. 73,# 43,p. 6138 - 6145] Location in patent:supporting information
624-31-7
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103-19-5
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$19.00/5g
106-38-7
403 suppliers
$14.00/5g
103-19-5
158 suppliers
$19.00/5g
637-60-5
312 suppliers
$6.00/5g
103-19-5
158 suppliers
$19.00/5g
