naproxen glucuronide synthesis

2synthesis methods

Product Name:naproxen glucuronide
CAS Number:41945-43-1
Molecular formula:C20H22O9
Molecular Weight:406.38

22204-53-1
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41945-43-1
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 67 percent / HATU; N-methylmorpholine / acetonitrile / 20 °C
2: 100 percent / cyclohexa-1,4-diene / Pd-C / tetrahydrofuran; propan-2-ol / 2 h / Heating

References:

Bowkett, Elizabeth R.;Harding, John R.;Maggs, James L.;Park, B. Kevin;Perrie, Jennifer A.;Stachulski, Andrew V. [Tetrahedron,2007,vol. 63,# 32,p. 7596 - 7605]

β-D-Glucopyranuronic acid, methyl ester, 1-[(αS)-6-methoxy-α-methyl-2-naphthaleneacetate]

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41945-43-1
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References