N-PHENYLCARBAZOLE HYDROCHLORIDE synthesis
- Product Name:N-PHENYLCARBAZOLE HYDROCHLORIDE
- CAS Number:1150-62-5
- Molecular formula:C18H13N
- Molecular Weight:243.3
Yield:1150-62-5 99%
Reaction Conditions:
with caesium carbonate;copper dichloride in acetonitrile at 0; for 4 h;Schlenk technique;
Steps:
1; 14
Add 0.2mmol (22mg) of substrate phenylhydrazine, 0.2mmol (33mg) of carbazole, 0.05mg (0.1mol%) of copper chloride, 130mg of cesium carbonate (4eq.), 2mL of acetonitrile to a 50mL Schlenk tube, and add magnets , The reaction was stirred at 0°C for 4h. After the reaction is over, add 50 mL of saturated brine, extract three times with 3*50 mL of dichloromethane, add anhydrous sodium sulfate to dry for 30 minutes, and then use a rotary evaporator to remove the low-boiling solvent. After the reaction liquid was vaporized by rotating and passed through the column, the target product was obtained with a yield of 99%.
References:
Xinxiang Runyu New Materials Technology Co., Ltd.;Li Heng;Geng Weizhi;Liang Helong;Zhou Yi;Zhang Yinlong;Liu Dongfang CN112010798, 2020, A Location in patent:Paragraph 0045-0048; 0099
