N-(4-Bromobutyl)phthalimide synthesis
- Product Name:N-(4-Bromobutyl)phthalimide
- CAS Number:5394-18-3
- Molecular formula:C12H12BrNO2
- Molecular Weight:282.13
Yield:5394-18-3 92.4%
Reaction Conditions:
in N,N-dimethyl-formamide; pH=10 at 20; for 26 h;
Steps:
1.4 preparation of intermediate 4
The phthalimide potassium salt (2.0g, 10 . 7mmol) with 1, 4 - dibromo butane (2.8g, 12 . 9mmol) dissolved in 25 ml dry N,N-dimethylformamide in, for pH 10, room temperature stirring 26h. Dichloromethane is used for extraction three times (100 ml × 3), washed with distilled water, combined with the organic layer, drying by anhydrous magnesium sulphate, concentrated, dichloromethane/distilled water recrystallization, filtering, drying to obtain the white solid, yield of 92.4%.
References:
Shandong University;Du Lvpei;Li Minyong;Wang Beilei CN104910894, 2017, B Location in patent:Paragraph 0032; 0034; 0042; 0043
24697-70-9
39 suppliers
inquiry
5394-18-3
283 suppliers
$5.00/1g
1147-76-8
23 suppliers
inquiry
5394-18-3
283 suppliers
$5.00/1g