METHYL THIOPHENE-3-ACETATE synthesis
- Product Name:METHYL THIOPHENE-3-ACETATE
- CAS Number:58414-52-1
- Molecular formula:C7H8O2S
- Molecular Weight:156.2
6964-21-2
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18107-18-1
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$33.00/5g
58414-52-1
84 suppliers
$30.00/250mg
Yield:-
Reaction Conditions:
Stage #1:thiophen-3-yl-acetic acid;diazomethyl-trimethyl-silane in methanol at 0; for 3 h;
Stage #2: with acetic acid in methanol
Steps:
41 Preparation of methyl 2-(thiophen-3-yl)acetate (E41)
Example 41 Preparation of methyl 2-(thiophen-3-yl)acetate (E41) To 2-(thiophen-3-yl)acetic acid in MeOH at 0° C. was added TMS-CH2N2. The solution was stirred for 3 hours then quenched with a few drops of AcOH. The solvents were evaporated. Column chromatography (SiO2, 3-15% EtOAc/Hex) gave pure methyl 2-(thiophen-3-yl)acetate (E41).
References:
deLong, Mitchell A.;Sturdivant, Jill Marie;Royalty, Susan M. US2010/22585, 2010, A1 Location in patent:Page/Page column 13-14
67-56-1
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6964-21-2
209 suppliers
$8.00/1g
58414-52-1
84 suppliers
$30.00/250mg
6964-21-2
209 suppliers
$8.00/1g
58414-52-1
84 suppliers
$30.00/250mg
6964-21-2
209 suppliers
$8.00/1g
79-22-1
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$38.00/1000g
58414-52-1
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$30.00/250mg
67237-53-0
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$19.89/250mg
67-56-1
756 suppliers
$7.29/5ml-f
58414-52-1
84 suppliers
$30.00/250mg