METHYL (E)-3-[4-(OCTYLOXY)PHENYL]-2-PROPENOATE synthesis
- Product Name:METHYL (E)-3-[4-(OCTYLOXY)PHENYL]-2-PROPENOATE
- CAS Number:99196-57-3
- Molecular formula:C18H26O3
- Molecular Weight:290.4
Yield:-
Reaction Conditions:
with potassium carbonate in ethyl acetate;acetone;
Steps:
6.2 Synthesis of Compound (1c)
2) 10 g (0.056 mol) of methyl p-hydroxycinnamate obtained in the step 1) above was dissolved in 50 ml of acetone; to which 7.8 g (0.057 mol) of potassium carbonate was added. To the obtained mixture, 12 g (0.062 mol) of 1-octylbromide was added, and refluxed with heating for 50 hours. After allowing the system to cool to room temperature, the obtained pellet was removed by filtration. Solvent was distilled off from the mother liquid of filtration, and the residue was dissolved in 100 ml of ethyl acetate, and washed with water. Solvent was further distilled off to obtain 15 g of yellowish white crystals. The crystals were recrystallized from hexane, and as a result, 14 g of methyl para-octyloxycinnamate was obtained as a white solid.
References:
US5505936,1996,A
