ChemicalBook CAS DataBase List METHYL 4-PYRROLIDIN-1-YLBENZOATE

METHYL 4-PYRROLIDIN-1-YLBENZOATE synthesis

12synthesis methods

Product Name:METHYL 4-PYRROLIDIN-1-YLBENZOATE
CAS Number:129414-26-2
Molecular formula:C12H15NO2
Molecular Weight:205.25

67-56-1 Synthesis

67-56-1
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$9.00/25ml

22090-27-3 Synthesis

22090-27-3
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$10.00/500mg

129414-26-2
56 suppliers
$68.00/1g

Yield:129414-26-2 95%

Reaction Conditions:

with thionyl chloride for 5 h;Reagent/catalyst;

Steps:

Esterification of p-Aminobenzoic Acida) With Thionyl Chloride and Methanol24

General procedure: To a solution of the benzoic acid derivative (10 mmol) in anhydrous methanol (35 mL)was added dropwise thionyl chloride (1.1 mL, 15 mmol) under vigorous stirring (stirbar). After 5 h, about 25 mL of the methanol was distilled off and the residue was pouredonto 50 mL of ice water. Then saturated aqueous sodium bicarbonate was added withstirring until the evolution of carbon dioxide ceased. The resulting precipitate wascollected and recrystallized from methanol.

References:

Pietrzak, Marek;J?drzejewska, Beata;M?drzejewska, Dorota;Bajorek, Agnieszka [Organic Preparations and Procedures International,2017,vol. 49,# 1,p. 45 - 52]

123-75-1 Synthesis