METHYL 3-CHLOROTHIOPHENE-2-CARBOXYLATE synthesis

2synthesis methods

22288-78-4 Synthesis

Yield: 70%

Reaction Conditions:

Stage #1:Methyl 3-aminothiophene-2-carboxylate with hydrogen cation;Nitrite
Stage #2: with copper(l) chlorideFurther stages.;

References:

Eller, Gernot A.;Haring, Andreas W.;Datterl, Barbara;Zwettler, Maryam;Holzer, Wolfgang [Heterocycles,2007,vol. 71,# 1,p. 87 - 104]

67-56-1 Synthesis

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