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ChemicalBook CAS DataBase List METHYL-2-BROMO-4-BROMOMETHYLBENZOATE
128577-48-0

METHYL-2-BROMO-4-BROMOMETHYLBENZOATE synthesis

2synthesis methods
87808-49-9 Synthesis
METHYL 2-BROMO-4-METHYLBENZOATE

87808-49-9
114 suppliers
$8.00/1g

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Yield: 94%

Reaction Conditions:

with tert.-butylhydroperoxide;cetyltrimethylammonim bromide;potassium bromide in water at 120; under 750.075 Torr;Microwave irradiation;

Steps:


General procedure: The reaction mixture was treated in a controlled microwavesynthesizer (Biotage Initiator+SP Wave model, 0-200 W at2.45 GHz, capped at 60 W during steady state) for severalminutes (the reaction attained 120 °C at 1 bar pressure). Thefinal products were isolated by column chromatographyusing an EtOAc-hexane gradient

References:

Reddy, Kancharla Rajendar;Rajanna, Kamatala C.;Venkateswarlu, Marri;Saiprakash [Synlett,2014,vol. 25,# 17,art. no. ST-2014-D0547-L,p. 2485 - 2487]

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