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ChemicalBook CAS DataBase List Levocetirizine Impurity 4
70558-10-0

Levocetirizine Impurity 4 synthesis

1synthesis methods
110-85-0 Synthesis
Piperazine

110-85-0
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13391-39-4 Synthesis
1-chloro-3-(chlorophenylmethyl)benzene

13391-39-4
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Yield:-

Reaction Conditions:

with potassium carbonate;potassium iodide in acetonitrile;Reflux;

References:

Pajouhesh, Hassan;Feng, Zhong-Ping;Ding, Yanbing;Zhang, Lingyun;Pajouhesh, Hossein;Morrison, Jerrie-Lynn;Belardetti, Francesco;Tringham, Elizabeth;Simonson, Eric;Vanderah, Todd W.;Porreca, Frank;Zamponi, Gerald W.;Mitscher, Lester A.;Snutch, Terrance P. [Bioorganic and Medicinal Chemistry Letters,2010,vol. 20,# 4,p. 1378 - 1383] Location in patent:scheme or table

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