Itraconazole Impurity 24 synthesis
- Product Name:Itraconazole Impurity 24
- CAS Number:79538-91-3
- Molecular formula:C21H25N5O2
- Molecular Weight:379.46
![3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-propyl-](/CAS/20200515/GIF/74852-92-9.gif)
74852-92-9
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Yield:79538-91-3 97%
Reaction Conditions:
with water;hydrogen bromide at 110; for 6 h;Inert atmosphere;
References:
Shi, Wei;Nacev, Benjamin A.;Aftab, Blake T.;Head, Sarah;Rudin, Charles M.;Liu, Jun O. [Journal of Medicinal Chemistry,2011,vol. 54,# 20,p. 7363 - 7374] Location in patent:supporting information; experimental part
38212-30-5
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79538-91-3
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74852-61-2
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![2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one](/CAS/GIF/74853-07-9.gif)
74853-07-9
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74852-62-3
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