INDANE-5-SULFONYL CHLORIDE synthesis
- Product Name:INDANE-5-SULFONYL CHLORIDE
- CAS Number:52205-85-3
- Molecular formula:C9H9ClO2S
- Molecular Weight:216.68
7790-94-5
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$51.00/5G
496-11-7
243 suppliers
$5.00/5g
52205-85-3
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$28.80/250mg
Yield:-
Reaction Conditions:
in dichloromethane;
Steps:
12; 13; 14 PREPARATION 12; Indane-5-sulfonamide
To a solution of indane (50 mmol, 6.11 mL) in dichloromethane (50 mL) at 0C is added dropwise chlorosulfonic acid (200 mmol, 13.3 mL). The resulting solution is allowed to return to room temperature and stirred for 2 hrs. The solution is then poured slowly onto a mixture of ice (200 g) and dichloromethane (50 mL). The organic layer is separated, washed with brine (50 mL), dried over sodium sulfate, filtered and evaporated to produce indan-5-sulfonic acid chloride.
References:
WO2004/48329,2004,A1 Location in patent:Page 13
496-11-7
243 suppliers
$5.00/5g
52205-85-3
50 suppliers
$28.80/250mg