Ethyl 4-(butylamino)benzoate synthesis
- Product Name:Ethyl 4-(butylamino)benzoate
- CAS Number:94-32-6
- Molecular formula:C13H19NO2
- Molecular Weight:221.3
123-72-8
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$12.32/25ML
94-09-7
779 suppliers
$5.00/50mg
94-32-6
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$18.00/25g
Yield: 90.49%
Reaction Conditions:
with 5%-palladium/activated carbon;hydrogen in methanol at 55; for 12 h;
Steps:
Example:
16.5 g of ethyl p-aminobenzoate and 7.2 g of n-butyraldehyde were placed in a hydrogenation reactor, and 118.6 g of methanol and 0.36 g of a 5% palladium carbon catalyst were added to raise the temperature to 55 degrees.The pressure is maintained at 6 kg, and hydrogen is supplied to carry out a hydrogenation reaction. After reacting for 12 hours, the pressure is reduced, the temperature is lowered, and the palladium carbon catalyst is separated by filtration, and the filtrate is recovered under reduced pressure to give a white solid. Dry product 20g, melting point mp68-69, product yield is 90.49%.
References:
Beijing Xuanguang Puli Biological Pharmaceutical Development Co., Ltd.;Xiao Gang CN109970583, 2019, A Location in patent:Paragraph 0006
99-77-4
215 suppliers
$12.00/1mg
123-72-8
423 suppliers
$12.32/25ML
94-32-6
191 suppliers
$18.00/25g
