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ChemicalBook CAS DataBase List ethyl 2-(4,4-difluorocyclohexyl)acetate
915213-54-6

ethyl 2-(4,4-difluorocyclohexyl)acetate synthesis

3synthesis methods
1283719-20-9 Synthesis
Acetic acid, 2-(4,4-difluorocyclohexylidene)-, ethyl ester

1283719-20-9
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Yield:915213-54-6 98%

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen in methanol at 20; under 750.075 Torr; for 16 h;

References:

Bamborough, Paul;Chung, Chun-Wa;Furze, Rebecca C.;Grandi, Paola;Michon, Anne-Marie;Watson, Robert J.;Mitchell, Darren J.;Barnett, Heather;Prinjha, Rab K.;Rau, Christina;Sheppard, Robert J.;Werner, Thilo;Demont, Emmanuel H. [Journal of Medicinal Chemistry,2018,vol. 61,# 18,p. 8321 - 8336]

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