DIISOPROPYL CYANOMETHYLPHOSPHONATE synthesis
- Product Name:DIISOPROPYL CYANOMETHYLPHOSPHONATE
- CAS Number:21658-95-7
- Molecular formula:C8H16NO3P
- Molecular Weight:205.19
116-17-6
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21658-95-7
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Yield:21658-95-7 78%
Reaction Conditions:
at 160; for 24 h;
Steps:
4
Chloroacetonitrile (145.7 g, 1.93 mols) and 380 ml of triisopropyl phosphite are mixed together and slowly heated up to 160° C. whereby the sideproducts are continuously distilled off. When the distillation has ceased, usually after 24 h, the residue is distilled at >120° C. and 0.2 mbar. Compound B is obtained in a yield of 78%.1H-NMR (300 MHz, CDCl3, ppm): 1.29-1.33 m, 12H, 2.72 d, 1H, 2.80 d, 1H; 4.67-4.79 m, 2H.31P-NMR (121 MHz, CDCl3, ppm): 13.10.
References:
US2009/123507,2009,A1 Location in patent:Page/Page column 15
35717-98-7
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21658-95-7
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1809-20-7
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21658-95-7
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