Diethoxydimethylsilane synthesis
- Product Name:Diethoxydimethylsilane
- CAS Number:78-62-6
- Molecular formula:C6H16O2Si
- Molecular Weight:148.28
14857-34-2
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1111-74-6
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78-62-6
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Yield:-
Reaction Conditions:
with sodium t-butanolate in tetrahydrofuran-d8 at 20; for 2 h;Sealed tube;Inert atmosphere;
Steps:
General procedure:
General procedure: Hydrosilane (0.4 mmol) was added to d8-THF (0.5 mL) in a dried J-Youngs NMR tube. Following a vigorous shake, nucleophile (2.5 mol%, 0.01 mmol) was added and the tube sealed, shaken and the NMR spectra quickly recorded. The NMR spectra were subsequently recorded at further time points to obtain overall reaction progress plots. Safety note: Given the hazardous nature of the gaseous product soften formed in these reactions, precautions should be taken when using any hydrosilane reagent, particularly in the absence of electrophile or metal-catalyst or if conducted on a large scale. J-Youngs NMR tubes containing hazardous product hydrosilanes were carefully opened and diluted with iPrOH (0.5 mL), then NaOH (2 M, 0.5 mL) to destroy remaining hydrosilanes.
References:
Docherty, Jamie H.;Dominey, Andrew P.;Thomas, Stephen P. [Tetrahedron,2019,vol. 75,# 24,p. 3330 - 3335]
64-17-5
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4098-30-0
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78-62-6
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75-78-5
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78-62-6
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78-10-4
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78-62-6
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