ChemicalBook CAS DataBase List D-tagatose

D-tagatose synthesis

9synthesis methods

Product Name:D-tagatose
CAS Number:87-81-0
Molecular formula:C6H12O6
Molecular Weight:180.16

Tagatose is obtained from D-galactose by isomerization under alkaline conditions in the presence of calcium.

59-23-4 Synthesis

59-23-4
657 suppliers
$6.00/25g

57-48-7 Synthesis

57-48-7
564 suppliers
$12.00/250G

87-81-0
368 suppliers
$12.50/5g

Yield:57-48-7 29% ，87-81-0 26%

Reaction Conditions:

with water in ethanol at 200; under 75007.5 Torr;Supercritical conditions;

Steps:

Isomerization or hydrolysis of saccharides in subcriticalaqueous ethanol

General procedure: Isomerization of each saccharidewas carried out in a continuous reaction system, inwhich the feed saccharide solution was delivered usingan LC-10AD VP HPLC pump (Shimadzu, Kyoto,Japan), into a stainless steel tubular reactor (0.8 mmI.D. × 1.0 m length) heated in a temperature-controlledsilicone oil bath (Dow Corning Toray Silicone, Tokyo,Japan). Upon exiting the reactor, the effluent wasdirectly introduced to a stainless steel tube immersed inan ice water bath in order to quench the reaction. Thepressure inside the reactor was regulated at ca. 10 MPaand reduced to ambient after cooling using a back-pressurevalve (Upchurch Scientific Inc., Oak Harbor, WA,USA). The residence time was set in the range of 50-500 s. The reaction temperature was set at 180-220 °C.Ethanol concentration was adjusted from 0 to 80 wt%and the substrate feed concentration ranged from 0.5 to5 wt% for maltose isomerization. For other saccharides,the reaction temperature was set at 200 °C; ethanolconcentration was adjusted at 0 (subcritical water) and60 wt% and the feed concentration was 0.5 wt%

References:

Gao, Da-Ming;Kobayashi, Takashi;Adachi, Shuji [Bioscience, Biotechnology and Biochemistry,2016,vol. 80,# 5,p. 998 - 1005]

50-99-7 Synthesis