Chloromethyl ethyl carbonate synthesis
- Product Name:Chloromethyl ethyl carbonate
- CAS Number:35179-98-7
- Molecular formula:C4H7ClO3
- Molecular Weight:138.55
22128-62-7
7 suppliers
$76.09/10g
35179-98-7
125 suppliers
$10.00/100mg
Yield:-
Reaction Conditions:
with triethylamine in ethanol;dichloromethane
Steps:
11 4-Phenyl-4-((4-carbo(ethoxycarbonyloxymethoxy) methylpiperazin-1-yl)carboxamido)piperidine hydrochloric acid salt
Combine chloromethyl chloroformate (19 mL) and ichloromethane (300 mL) and cool in an ice bath. Add dropwise over about i hour, a solution of ethanol (11.7 mL and triethylamine (30.7 mL) in dichloromethane (100 mL). After 3.5 hours, filter and concentrate the filtrate to give a residue. Partition the residue between diethyl ether and water. Separate the organic layer and dry over MgSOA, filter and evaporate in vacuo to give ethyl chloromethyl carbonate.
References:
Hoechst Marion Roussel, Inc. US5977139, 1999, A
64-17-5
727 suppliers
$10.00/50g
22128-62-7
7 suppliers
$76.09/10g
35179-98-7
125 suppliers
$10.00/100mg
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
0 suppliers
inquiry
35179-98-7
125 suppliers
$10.00/100mg