ChemicalBook CAS DataBase List BROMOMETHYLENECYCLOHEXANE 96

BROMOMETHYLENECYCLOHEXANE 96 synthesis

10synthesis methods

Product Name:BROMOMETHYLENECYCLOHEXANE 96
CAS Number:1121-49-9
Molecular formula:C7H11Br
Molecular Weight:175.07

60014-85-9
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1121-49-9
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Yield:1121-49-9 92%

Reaction Conditions:

with potassium carbonate;Dimethyl phosphite in 1,4-dioxane at 80; for 13 h;Inert atmosphere;

Steps:

General Procedure for Reduction of Gem-Dibromides with DimethylPhosphite and Potassium Carbonate. General procedure:

General procedure: An oven-dried glass tube containing an Teflon-coated stir bar was charged with a mixture of dibromide (0.2 mmol), (MeO)2P(O)H (0.4 mmol), and K2CO3 (0.2 mmol) in 0.4 mL of dioxane under N2 atmosphere and stirred at 80°C for 13 h. After the reaction, Na2CO3 saturated solution (1 mL) was added to the reaction mixture, and extracted with ethyl acetate. The combined organic extracts were dried over anhydrous Na2SO4, concentrated in vacuum, and the resulting residue was purified by GPC to afford the pure products.

References:

Zhao, Yalei;Chen, Tieqiao;Wang, Xiang-Bo;Han, Li-Biao [Phosphorus, Sulfur and Silicon and the Related Elements,2015,vol. 190,# 11,p. 1820 - 1827]

1034-49-7 Synthesis