bis(3',5')-cyclic diguanylic acid synthesis
- Product Name:bis(3',5')-cyclic diguanylic acid
- CAS Number:61093-23-0
- Molecular formula:C20H24N10O14P2
- Molecular Weight:690.41
81279-39-2
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61093-23-0
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Yield:-
Steps:
Multi-step reaction with 5 steps
1.1: 100 percent / pyridinium trifluoroacetate / nitromethane / 1 h / 20 °C
2.1: pyridinium trifluoroacetate / acetonitrile / 0.5 h / 20 °C
2.2: 89 percent / tert-butylhydroperoxide / acetonitrile / 0.5 h / 20 °C
3.1: 91 percent / Amberlite IR-120 sulfonic acid resin / methanol / 0.25 h
4.1: adamantoylcarbonyl chloride / pyridine / 0.03 h / 20 °C
4.2: 80 percent / N-bromosuccinimide / pyridine / 0.25 h / 20 °C
5.1: 79 percent / aq. NH3 / pyridine / 48 h
References:
Zhang, Zhaoying;Gaffney, Barbara L.;Jones, Roger A. [Journal of the American Chemical Society,2004,vol. 126,# 51,p. 16700 - 16701]
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118684-41-6
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61093-23-0
88 suppliers
$131.00/500ug